Samenvatting
A multiple hydrogen-bond array based on dipyrimidin-2-ylamine is presented, which is easily accessible. The influence of a preorganizing intramolecular hydrogen bond, tautomeric equilibria, and steric effects on the association behavior were investigated. X-ray diffraction shows that the molecules feature an ADA (acceptor-donor-acceptor) array of hydrogen-bonding sites in the solid state. The array persists in solution, and H-1 NMR titrations show that molecules with sterically nondemanding DAD arrays are selectively bound.
Originele taal-2 | Engels |
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Pagina's (van-tot) | 3887-3889 |
Tijdschrift | Organic Letters |
Volume | 3 |
Nummer van het tijdschrift | 24 |
DOI's | |
Status | Gepubliceerd - 2001 |