• 23 Citaten
20182019
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Persoonlijk profiel

Quote

"A person who never made a mistake never tried anything new" - Albert Einstein

Research profile

Nikita Subedi is Doctoral Candidate in the group of immunoengineering under the supervision of Dr. Jurjen Tel. Her research focuses on understanding cellular interaction in immune cells.  She works on developing a Microfluidic droplet based single cell analysis platform to study different effector functions that are generated as a result of interaction of immune cells with their partner cells or molecules. 

Academic background

Nikita Subedi (1990) is from Kathmandu, Nepal. She did her bachelors in Biotechnology, from Kathmandu University, Nepal in 2012. She completed her masters as MSc in Molecular Mechanisms of Diseases from Radboud UMC in 2016. As a part of her master’s training, she worked in two different laboratories, one in RIMLS, Radboud UMC, Nijmegen and the other in DFCI, Harvard Medical School, Boston both of them working in immunology. In Nijmegen she studied plasmacytoid dendritic cells with the group of Dr. Jurjen Tel in understanding the functional heterogeinity within these immune subsets. Her project in DFCI was about developing nanoparticle targeting check point inhibitors like PD1 molecules in T cells thus boosting the T cell mediated cytotoxicity. She joined the group of immunoengineering in 2017 to continue as as PhD candidate in the feild.

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  • 1 Vergelijkbare profielen
Single-Cell Analysis Medicijnen en Levenswetenschappen
Microfluidics Medicijnen en Levenswetenschappen
Cloud seeding Chemische stoffen
Paracrine Communication Medicijnen en Levenswetenschappen
interferon Fysica en Astronomie
Interferon Type I Medicijnen en Levenswetenschappen
Allergy and Immunology Medicijnen en Levenswetenschappen
Interferon-alpha Medicijnen en Levenswetenschappen

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Onderzoeksoutput 2018 2019

  • 23 Citaten
  • 2 Tijdschriftartikel
  • 1 Artikel recenseren
2 Citaties (Scopus)
19 Downloads (Pure)

A pipette-tip based method for seeding cells to droplet microfluidic platforms

Sinha, N., Subedi, N., Wimmers, F., Soennichsen, M. & Tel, J., 11 feb 2019, In : Journal of Visualized Experiments (JoVE). 144, 10 blz., e57848.

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

Open Access
Bestand
Cloud seeding
Microfluidics
Encapsulation
Poisson distribution
Poisson Distribution
2 Citaties (Scopus)
114 Downloads (Pure)

Integrating immunology and microfluidics for single immune cell analysis

Sinha, N., Subedi, N. & Tel, J., 16 okt 2018, In : Frontiers in Immunology. 9, 16 blz., 2373.

Onderzoeksoutput: Bijdrage aan tijdschriftArtikel recenserenAcademicpeer review

Open Access
Bestand
Single-Cell Analysis
Microfluidics
Allergy and Immunology
Immune System
Point-of-Care Systems
19 Citaties (Scopus)
58 Downloads (Pure)

Single-cell analysis reveals that stochasticity and paracrine signaling control interferon-alpha production by plasmacytoid dendritic cells

Wimmers, F., Subedi, N., van Buuringen, N., Heister, D., Vivié, J., Beeren-Reinieren, I., Woestenenk, R., Dolstra, H., Piruska, A., Jacobs, J. F. M., van Oudenaarden, A., Figdor, C. G., Huck, W. T. S., de Vries, I. J. M. & Tel, J., 1 dec 2018, In : Nature Communications. 9, 1, 12 blz., 3317.

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

Open Access
Bestand
Paracrine Communication
interferon
Single-Cell Analysis
Interferon Type I
Interferon-alpha

Scriptie

Probing macrophage plasticity and heterogeneity using microfluidic single-cell encapsulation and multicolor flow cytometry

Auteur: Tiemeijer, B., 25 apr 2019

Begeleider: Tel, J. (Afstudeerdocent 1), Smits, A. (Afstudeerdocent 2) & Subedi, N. (Afstudeerdocent 2)

Scriptie/masterproef: Master