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Persoonlijk profiel

Onderwijs en Doceren

6EMA54 Physical chemistry of Soft Matter (Teaching Assistant)

Quote

Collagen and silica are an ideal match to produce scaffolds for biomedial applications.

Academic background

Onderwijs en Doceren

Research profile

Type I collagen is the most abundant component of the extracellular matrix. Its biocompatibility makes it ideal for synthesis of biomaterials, but its lack of mechanical resistance is a drawback. Silica seems to be an ideal partner to collagen to overcome this problem. Silica-collagen scaffolds are promising materials for the development of biomedical devices for tissue engineering, as silicon has a stimulating effect on osteogenesis.

The mineralization of collagen with silica has been studied for many years and silica-collagen scaffolds have already been used for the growth of fibroblasts and osteoblasts.  However, very little is known on how these two materials interact and how the intrafibrillar infilatrion can be achieved.

Understanding this would allow us to design materials with tunable mechanical properties and biocompatibility. Moreover, the possibility to use collagen for 3D printing opens the way construct hybrid materials with multiple hierarchical levels, just as we find in biological materials.

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Onderzoeksoutput

  • 48 Citaties
  • 2 Tijdschriftartikel
  • 1 Poster

Liquid–liquid phase separation during amphiphilic self-assembly

Ianiro, A., Wu, H., van Rijt, M. M. J., Vena, M. P., Keizer, A. D. A., Esteves, A. C. C., Tuinier, R., Friedrich, H., Sommerdijk, N. A. J. M. & Patterson, J. P., 1 apr 2019, In : Nature Chemistry. 11, 4, blz. 320-328 9 blz.

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

Open Access
Bestand
  • 29 Citaten (Scopus)
    182 Downloads (Pure)

    Formation and mineralization of nanoparticles with bicontinuous internal structure

    Vena, M. P., Patterson, J. P. & Sommerdijk, N. A. J. M., 2017.

    Onderzoeksoutput: Bijdrage aan congresPosterAcademic

    Microorganism mediated biosynthesis of metal chalcogenides: a powerful tool to transform toxic effluents into functional nanomaterials

    Vena, M. P., Jobbágy, M. & Bilmes, S. A., 15 sep 2016, In : Science of the Total Environment. 565, blz. 804-810

    Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

  • 19 Citaten (Scopus)