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Persoonlijk profiel


I use big microscopes to look at small objects.

Research profile

Lorenzo Albertazzi is an associate professor at the TU/e department of Biomedical Engineering (research group Molecular Biosensing for Medical Diagnostics). He is also junior group leader at the Institute of Bioengineering of Catalonia (IBEC) in Barcelona, where he leads the 'Nanoscopy for Nanomedicine' group. For most of his career he has been jumping between Chemistry and Biophysics; in his research he now aims to combine both to achieve a molecular understanding of synthetic materials in the biological environment, using optical microscopy and nanoscopy.

With his 2017 ERC Starting Grant, Lorenzo aims at the 'Design of Nanomaterials for Targeted Therapies Guided by Super Resolution Imaging'. In the NANOSTORM project he plans to use super resolution microscopy to examine nanomaterials that have potential as cancer therapies, and understand their interactions with their target: the diseased cells. Doing so will help identify the key principles that are needed to rationally design the next generation of targeted, super-efficient cancer treatments

Academic background

Lorenzo Albertazzi obtained a MSc in Chemistry (2007) and a PhD in Biophysics (2011) from Scuola Normale Superiore (Pisa, Italy). He then joined Eindhoven University of Technology (TU/e, The Netherlands) as postdoctoral researcher. In 2013, he was awarded a fellowship of the Institute for Complex Molecular Systems (ICMS) at TU/e, and in 2014 he became a NWO/VENI fellow (2014). In 2015, he moved to Barcelona (Spain) to the Institute of Bioengineering of Catalonia (IBEC) to start the 'Nanoscopy for Nanomedicine' group that he currently leads. In 2017, he received an ERC starting grant and in 2018 he was appointed Associate Professor at the TU/e department of Biomedical Engineering, with the research group Molecular Biosensing.

Vingerafdruk Duik in de onderzoeksthema's waar Lorenzo Albertazzi actief is. Deze onderwerplabels komen voort uit het werk van deze persoon. Samen vormen ze een unieke vingerafdruk.

  • 10 Vergelijkbare profielen
Microscopic examination Chemische stoffen
Polymers Chemische stoffen
Dendrimers Chemische stoffen
Nanoparticles Chemische stoffen
Imaging techniques Chemische stoffen
Water Chemische stoffen
Cells Chemische stoffen
Microscopy Medicijnen en Levenswetenschappen

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Onderzoeksoutput 2009 2019

  • 2424 Citaten
  • 61 Tijdschriftartikel
  • 3 Artikel recenseren
  • 1 Poster
5 Citaties (Scopus)
39 Downloads (Pure)

A stochastic view on surface inhomogeneity of nanoparticles

Post, R. A. J., van der Zwaag, D., Bet, G., Wijnands, S. P. W., Albertazzi, L., Meijer, E. W. & van der Hofstad, R. W., 10 apr 2019, In : Nature Communications. 10, 1, 11 blz., 1663.

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

Open Access
Microscopic examination
1 Citaat (Scopus)
14 Downloads (Pure)

Efficient small-scale conjugation of DNA to primary antibodies for multiplexed cellular targeting

Cremers, G., Rosier, B., Riera Brillas, R., Albertazzi, L. & de Greef, T., 18 sep 2019, In : Bioconjugate Chemistry. 30, 9, blz. 2384-2392 9 blz.

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

Open Access
Affinity Labels
2 Citaties (Scopus)
2 Downloads (Pure)

Quantifying guest–host dynamics in supramolecular assemblies to analyze their robustness

Bastings, M. M. C., Hermans, T. M., Spiering, A. J. H., Kemps, E. W. L., Albertazzi, L., Kurisinkal, E. E. & Dankers, P. Y. W., 1 jan 2019, In : Macromolecular Bioscience. 19, 1, 11 blz., 1800296.

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

Supramolecular chemistry
Fluorescence Recovery After Photobleaching
Fluorescence Resonance Energy Transfer
3 Citaties (Scopus)
42 Downloads (Pure)

Super-resolution imaging of structure, molecular composition, and stability of single oligonucleotide polyplexes

Feiner-Gracia, N., Olea, R. A., Fitzner, R., El Boujnouni, N., van Asbeck, A. H., Brock, R. & Albertazzi, L., 8 mei 2019, In : Nano Letters. 19, 5, blz. 2784-2792 9 blz.

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

Open Access
Cell-Penetrating Peptides
Molecular structure
10 Citaties (Scopus)

Super-resolution microscopy as a powerful tool to study complex synthetic materials

Pujals, S., Feiner-Gracia, N., Delcanale, P., Voets, I. & Albertazzi, L., 1 feb 2019, In : Nature Reviews Chemistry. 3, 2, blz. 68-84 17 blz.

Onderzoeksoutput: Bijdrage aan tijdschriftArtikel recenserenAcademicpeer review

Microscopic examination
Biocompatible Materials
Materials science


Nanostructured materials
Imaging techniques
Microscopic examination
Drug delivery
Intelligent materials

Personalized attack on cancer cells

Lorenzo Albertazzi (Ontvanger), 2019

Prijs: NWOVidiWetenschappelijk

Biomedical Engineering
Pharmaceutical Preparations


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Binding a BTA fiber to dsDNA via intercalation

Auteur: Visser, P., 31 aug 2015

Begeleider: Baker, M. (Afstudeerdocent 1), Albertazzi, L. (Afstudeerdocent 2) & Meijer, E. (Afstudeerdocent 2)

Scriptie/masterproef: Master


Crosslinking supramolecular polymers : gaining control over dynamics

Auteur: Hoogland, D., 31 aug 2014

Begeleider: Albertazzi, L. (Afstudeerdocent 1) & Meijer, E. (Afstudeerdocent 2)

Scriptie/masterproef: Master

Enzyme-responsive supramolecular polymers

Auteur: van der Veeken, N., 31 jan 2015

Begeleider: Albertazzi, L. (Afstudeerdocent 1), Meijer, E. (Afstudeerdocent 2), de Greef, T. (Afstudeerdocent 2) & Merkx, M. (Afstudeerdocent 2)

Scriptie/masterproef: Master

Exploring multistep non-covalent synthesis: investigating supramolecular host-guest assemblies

Auteur: Goor, O., 31 mei 2013

Begeleider: Bastings, M. (Afstudeerdocent 1), Albertazzi, L. (Afstudeerdocent 2) & Dankers, P. (Afstudeerdocent 2)

Scriptie/masterproef: Master