Persoonlijk profiel
Quote
Nature is stunningly beautiful, mysteriously complex and so effective that learning from it is pure joy.
Research profile
Jan de Boer is full professor at the department of Biomedical Engineering, where he leads the research group BioInterface Science. He is an experienced University Professor and Chief Scientific Officer with a demonstrated history of working in academia and biotech. As a research professional he is skilled in Stem Cells, Biomaterial Engineering and Regenerative Medicine.
Jan is interested in the molecular complexity of cells and how molecular circuits are involved in cell and tissue function. With a background in mouse and Drosophila genetics, he entered the field of biomedical engineering in 2002 and has since focused on understanding and implementing molecular biology in the field of tissue engineering and regenerative medicine. His research is characterized by a holistic approach to both discovery and application, aiming at combining high throughput technologies, computational modeling and experimental cell biology, to streamline the wealth of biological knowledge to real clinical applications.
Academic background
Jan de Boer obtained his MSc degree Biology at Utrecht University in 1994. He then started his PhD research in the lab of Prof. Jan Hoeijmakers on the genetics of ageing at the department of Cell Biology and Genetics, Erasmus University Rotterdam. Next, he moved to the MRC Laboratory of Molecular Biology (Cambridge, UK) where he worked as postdoctoral research fellow in Drosophila genetics. He returned to the Netherlands in 2002 to become a senior research scientist at the biotech company IsoTis, which was founded by Prof. Clemens van Blitterswijk with whom he collaborated until October 2018 when he moved to Eindhoven. In 2003, he became associate professor at the University of Twente and was awarded an NWO-VIDI grant in 2007. In 2012/2013 he spent a year as visiting scientist at the Broad Institute and Wyss Institute in Boston, MA, USA. In 2014, Jan de Boer was appointed full professor of Cell Biology-inspired Tissue Engineering at the Merln Institute of Maastricht University. Jan de Boer is co-founder and Chief Scientific Officer of the biotech company Materiomics, established in 2009 as a spin-off of his work at the University of Twente. Materiomics exploits the 'TopoChip' technology to design and identify the best surface for improved functionality and durability of medical and cell culture devices.
Externe posities
CSO and founder Materiomics b.v.
10 dec. 2006 → …
Expertise gerelateerd aan duurzame ontwikkelingsdoelstellingen van de VN
In 2015 stemden de VN-lidstaten in met 17 wereldwijde duurzame ontwikkelingsdoelstellingen (Sustainable Development Goals, SDG's) om armoede te beëindigen, de planeet te beschermen en voor iedereen welvaart te garanderen. Het werk van deze persoon draagt bij aan de volgende duurzame ontwikkelingsdoelstelling(en):
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SDG 3 – Goede gezondheid en welzijn
Vingerafdruk
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
Onderzoeksoutput
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Controllable Dynamic Mechanical Cell Stimulation using Magnetically Actuated Artificial Cilia
Kooi, R., Ul Islam, T., Stassen, O. M. J. A., Amsing, N., de Boer, J. & den Toonder, J. M. J. (Corresponding author), 1 feb. 2026, (E-publicatie vóór gedrukte publicatie) In: Advanced Healthcare Materials. XX, e00001.Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review
Open Access -
Controlling spatial organization of the cell - using surface micro-pillar patterns to manipulate Golgi morphology and function
Verbakel, J. & de Boer, J. (Corresponding author), 16 mrt. 2026, In: Journal of Cell Science. 139, 5Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review
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Immunomodulatory topographies regulate myofibroblast differentiation and influence fibrous encapsulation of glaucoma drainage devices
Sudarsanam, P. K., van Mechelen, R. J. S., Kuijpers, T. J. M., Bertens, C. J. F., Alsema, E., Verbakel, J., Beijer, N. R. M., Beckers, H. J. M. & de Boer, J. (Corresponding author), jun. 2026, In: Bioactive Materials. 60, blz. 492-509 18 blz.Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review
Open AccessBestand42 Downloads (Pure) -
The Floor-Ceiling-Chip, or 2 × 2D = Pseudo-3D—Approaching 3D Cell Morphology and Organization between Two Opposing 2D Substrates with Cell-Adhesive Protein Micropatterns
Tuvshindorj, U., Giacomini, F., Kaçmaz, E. G., ten Brink, T., Moroni, L., Birgani, Z. T., van Blitterswijk, C., Habibović, P., Giselbrecht, S., de Boer, J. & Truckenmüller, R. (Corresponding author), 17 mrt. 2026, (E-publicatie vóór gedrukte publicatie) In: Advanced Healthcare Materials. XXOnderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review
Open Access -
Acquisition, quality control, and architecture of a large image dataset as a tool for in silico cell biological research
Konshin, N. (Corresponding author), Valverde, M. G., Solodennikov, D., Minartz, K., Menkovski, V., Masereeuw, R., Singh, S., Mihăilă, S. M. & de Boer, J. (Corresponding author), dec. 2025, In: Materials Today Bio. 35, 18 blz., 102352.Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review
Open AccessBestand39 Downloads (Pure)
Datasets
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Micro-topographies induce epigenetic reprogramming and quiescence in human mesenchymal stem cells
Vermeulen, S. A. A. (Ontwerper), de Boer, J. (Ontwerper) & Hebels, D. G. A. J. (Bijdrager), DataverseNL, 7 nov. 2022
DOI: 10.34894/s2qx6c, https://dataverse.nl/citation?persistentId=doi:10.34894/S2QX6C
Dataset
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Mechanotransduction is a context-dependent activator of TGF-β signaling in mesenchymal stem cells
Vermeulen, S. A. A. (Ontwerper), de Boer, J. (Bijdrager) & Hebels, D. (Bijdrager), DataverseNL, 18 aug. 2020
DOI: 10.34894/vvatm8, https://dataverse.nl/citation?persistentId=doi:10.34894/VVATM8
Dataset
Cursussen
Knipsels
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Eindhoven University of Technology Reports Findings in Biology (The Influence of Design Modifications and Microstructured Surface Topographies on Bleb Survival after Glaucoma Tube Shunt Implantation)
10/05/23
1 item van Media-aandacht
Pers / media: Vakinhoudelijk commentaar
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Eindhoven University of Technology: Jan De Boer - 'A Research Expedition Like Tintin in South America!'
21/12/21
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Pers / media: Vakinhoudelijk commentaar
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Jan de Boer: “A research expedition like Tintin in South America!”
21/12/21
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Pers / media: Vakinhoudelijk commentaar
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Netherlands : Karen Aardal and Rob Hamer new board members of NWO Domain Science 17 June 2021
19/06/21
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Pers / media: Vakinhoudelijk commentaar
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US Patent Issued to UNIVERSITEIT TWENTE on March 30 for "VHH for application in tissue repair, organ regeneration, organ replacement and tissue engineering" (Dutch Inventors)
5/04/21
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Pers / media: Vakinhoudelijk commentaar