Projecten per jaar
Persoonlijk profiel
Quote
“One of the most fascinating scientific trends of today is the merging of technology and biology: new technological solutions are inspired by biology, and technology is used to study, understand, and even steer biological processes.”
Research profile
Jaap den Toonder is full professor and Chair of the Microsystems research Section at Eindhoven University of Technology (TU/e). His group focuses its research on the investigation and development of innovative technological concepts, fabrication methods, and interactive polymer materials for microsystems for a wide range of applications. The application focus is on microfluidic chips, biomedical microdevices, and soft microrobotics. The group’s research approaches are often biologically inspired, translating principles from nature into technological innovations.
Den Toonder’s main personal research interests are microfluidics, nature-inspired micro-actuators, smart medical microdevices, and organs-on-chips to understand cancer. Den Toonder teaches courses on microfabrication methods, microfluidics, and heat and flow in microsystems, in which hands-on learning is a key element. He received an ERC Advanced Grant in 2019. Den Toonder was elected Fellow of the Netherlands Academy of Engineering in 2023.
Academic background
Jaap den Toonder studied at Delft University of Technology where he obtained his MSc in Applied Mathematics (cum laude). He received his PhD (cum laude) from the same university on a numerical/theoretical and experimental study of drag reduction in turbulent flows by polymer additives. In 1995, he joined Philips Research Laboratories in Eindhoven, and began working in mechanics of solid materials. He worked on a wide variety of applications, such as ceramic capacitors, optical storage systems, IC low-k materials, RF MEMS, soft electronics, biomedical devices, polymer MEMS, and micro-fluidics. In 2008, he became Chief Technologist, leading the R&D program on (micro-)fluidics, and (starting 2011) materials science and engineering. He was involved in research programs on molecular diagnostics, lab-on-chip, immersion lithography and energy applications.
Next to his main job at Philips, he was a part-time professor of Microfluidics Technology at Eindhoven University of Technology between 2004 and 2013.
Affiliated with
- Member of the Executive Board of the human organ and Disease Model Technologies Institute (hDMT)
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Scientific advisor of AZAR Innovations
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Scientific advisor of ShanX Medtex
- Scientific advisor of InnoFluidics
Main partners in (semi-)industry
- Philips
- ASML
- Micronit
- TNO
- IMEC
- Santen-Innfocus
- DEMCON
Expertise gerelateerd aan duurzame ontwikkelingsdoelstellingen van de VN
In 2015 stemden de VN-lidstaten in met 17 wereldwijde duurzame ontwikkelingsdoelstellingen (Sustainable Development Goals, SDG's) om armoede te beëindigen, de planeet te beschermen en voor iedereen welvaart te garanderen. Het werk van deze persoon draagt bij aan de volgende duurzame ontwikkelingsdoelstelling(en):
Vingerafdruk
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
Projecten
- 3 Afgelopen
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bOne metaStatis chip with microphysiological Circulation for cAncer pRofiling LSHI22004
den Toonder, J. M. J. (Project Manager)
1/04/23 → 30/09/24
Project: Third tier
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Accelerating Innovation in Microfabricated Medical Devices
den Toonder, J. M. J. (Project Manager), Jouy Bar, M. (Projectmedewerker) & Wang, Y. (Projectmedewerker)
1/06/20 → 30/09/23
Project: Onderzoek direct
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Magnetic control of micro-particles and integrated micro-actuators for high precision handheld diagnostics
den Toonder, J. M. J. (Project Manager) & Shanko, E. (Projectmedewerker)
1/11/16 → 31/10/20
Project: Onderzoek direct
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Magnetically actuated glaucoma drainage device for regulating intraocular pressure after implantation
Pereira, I. C. F., van Mechelen, R., Wyss, H. M., Pinchuk, L., Beckers, H. J. M. & den Toonder, J. M. J. (Corresponding author), 20 jul. 2023, In: Microsystems & Nanoengineering. 9, 15 blz., 92.Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review
Open AccessBestand4 Citaten (Scopus)95 Downloads (Pure) -
Highly motile nanoscale magnetic artificial cilia
Ul Islam, T., Bellouard, Y. J. & den Toonder, J. M. J. (Corresponding author), 31 aug. 2021, In: Proceedings of the National Academy of Sciences of the United States of America (PNAS). 118, 35, 7 blz., e2104930118.Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review
Open AccessBestand20 Citaten (Scopus)96 Downloads (Pure) -
An artificial aquatic polyp that wirelessly attracts, grasps, and releases objects
Pilz da Cunha, M., Kandail, H. S., den Toonder, J. M. J. (Corresponding author) & Schenning, A. P. H. J. (Corresponding author), 28 jul. 2020, In: Proceedings of the National Academy of Sciences of the United States of America (PNAS). 117, 30, blz. 17571-17577 7 blz.Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review
Open Access38 Citaten (Scopus) -
Removal of microparticles by ciliated surfaces: an experimental study
Zhang, S., Wang, Y., Onck, P. R. & den Toonder, J. M. J. (Corresponding author), 8 feb. 2019, In: Advanced Functional Materials. 29, 6, 11 blz., 1806434.Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review
Open AccessBestand46 Citaten (Scopus)309 Downloads (Pure) -
A novel method to understand tumor cell invasion: integrating extracellular matrix mimicking layers in microfluidic chips by "selective curing"
Eslami Amirabadi, H., Sahebali, S., Frimat, J. M. S., Luttge, R. & den Toonder, J. M. J., 17 okt. 2017, In: Biomedical Microdevices. 19, 4, 11 blz., 19:92.Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review
Open AccessBestand21 Citaten (Scopus)235 Downloads (Pure)
Datasets
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Microfluidic Models of Metastasis: In vitro approaches to study the tumor microenvironment - supplementary design and video files
Sleeboom, J. (Ontwerper), Sahlgren, C. M. (Ontwerper) & den Toonder, J. M. J. (Ontwerper), 4TU.Centre for Research Data, 21 aug. 2020
DOI: 10.4121/uuid:08ac69b6-6430-4ffa-a33e-40da88821dc6
Dataset
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Data underlying the publication "A biomimetic microfluidic model to study signalling between endothelial and vascular smooth muscle cells under hemodynamic conditions"
van Engeland, N. C. A. (Bijdrager), Pollet, A. (Ontwerper), den Toonder, J. M. J. (Bijdrager), Bouten, C. V. C. (Ontwerper), Stassen, O. M. J. A. (Ontwerper) & Sahlgren, C. M. (Ontwerper), 4TU.Centre for Research Data, 2 sep. 2020
DOI: 10.4121/12854756, https://data.4tu.nl/articles/_/12854756
Dataset
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Source data for the publication: Controlled multidirectional particle transportation by magnetic artificial cilia
Zhang, S. (Bijdrager), Zhang, R. (Bijdrager), Wang, Y. (Bijdrager), Onck, P. R. (Bijdrager) & den Toonder, J. M. J. (Bijdrager), 4TU.Centre for Research Data, 30 mei 2022
DOI: 10.4121/19915390
Dataset
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Source data for the publication: Engineered modular microphysiological models of the human airway clearance phenomena
den Toonder, J. (Bijdrager), 4TU.Centre for Research Data, 30 mei 2022
DOI: 10.4121/19923707, https://data.4tu.nl/articles/_/19923707
Dataset
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Source data for the publication: Anti-Biofouling and Self-Cleaning Surfaces Featured with Magnetic Artificial Cilia
Zhang, S. (Bijdrager), Zuo, P. (Bijdrager), Wang, Y. (Bijdrager), Onck, P. (Bijdrager), den Toonder, J. M. J. (Bijdrager) & Toonder, J. M. J. D. (Bijdrager), 4TU.Centre for Research Data, 30 mei 2022
DOI: 10.4121/19915330
Dataset
Prijzen
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Unraveling forces on cells with artificial microscopic hairs
den Toonder, J. (Ontvanger), 29 mrt. 2019
Prijs: ERC › Advanced › Wetenschappelijk
Cursussen
Knipsels
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New Findings from Eindhoven University of Technology in the Area of Science Published (Miniaturized metachronal magnetic artificial cilia)
Wang, T., Cui, Z., den Toonder, J. M. J. & Wang, Y.
7/09/23
1 item van Media-aandacht
Pers / media: Vakinhoudelijk commentaar
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-Eindhoven University of Technology: Major EU grants for groundbreaking research into scoliosis and transplant organ rejection
Ito, K., Mulder, W. J. M., den Toonder, J. M. J. & Bakkers, E. P. A. M.
23/04/21
1 item van Media-aandacht
Pers / media: Vakinhoudelijk commentaar
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Major EU grants for groundbreaking research into scoliosis and transplant organ rejection
Ito, K., Mulder, W. J. M., den Toonder, J. M. J. & Bakkers, E. P. A. M.
22/04/21
1 item van Media-aandacht
Pers / media: Vakinhoudelijk commentaar
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-TU/e involved in all six Perspectief programs
Govaert, L. E., Voeten, J. P. M., den Toonder, J. M. J., Nijmeijer, K. & Kok, J. K.
11/03/21
1 item van Media-aandacht
Pers / media: Vakinhoudelijk commentaar
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-TU Delft and partners to create superhighway for digital data:
den Toonder, J. M. J. & Kok, J. K.
11/03/21
1 item van Media-aandacht
Pers / media: Vakinhoudelijk commentaar