Persoonlijk profiel

Academic background

Arjan Hazegh Nikroo (Helmond, 1996) obtained his Bachelor and Master degree in Biomedical Engineering at Eindhoven University of Technology in 2018 and 2022, respectively. For his master thesis in the Chemical Biology group of prof. Luc Brunsveld, he engineered phosphoregulated scaffold proteins by fusing 14-3-3 proteins to inhibitory peptide modules that reversibly block and liberate the 14-3-3 binding pockets via phosphorylation and dephosphorylation. During a subsequent internship at Ambagon Therapeutics, he developed a fluorescence polarization multiplex selectivity assay for compounds that stabilize 14-3-3 protein-protein interactions. Arjan completed his degree with an additional internship at the Discovery & Technology department of MSD Boxmeer. There, he focused on the recombinant expression, purification and characterization of monomeric and dimeric antigen-specific IgA monoclonal antibodies.

As of May 2022, Arjan is a PhD candidate in the Bio-Organic Chemistry group of prof. Jan van Hest. His research is centered on the bottom-up engineering of protein-mediated communication between coacervate-based synthetic cells and living cells. To this end, he applies protein engineering and synthetic biology techniques to develop systems that impart controllability over protein uptake and release in synthetic cells, while also integrating biofunctional proteins, such as cytokines, to elicit desired responses in living cells.

Expertise gerelateerd aan duurzame ontwikkelingsdoelstellingen van de VN

In 2015 stemden de VN-lidstaten in met 17 wereldwijde duurzame ontwikkelingsdoelstellingen (Sustainable Development Goals, SDG's) om armoede te beëindigen, de planeet te beschermen en voor iedereen welvaart te garanderen. Het werk van deze persoon draagt bij aan de volgende duurzame ontwikkelingsdoelstelling(en):

  • SDG 3 – Goede gezondheid en welzijn

Vingerafdruk

Verdiep u in de onderzoeksgebieden waarop Arjan Hazegh Nikroo actief is. Deze onderwerplabels komen uit het werk van deze persoon. Samen vormen ze een unieke vingerafdruk.
  • 1 Soortgelijke profielen

Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar

Recente externe samenwerking op landen-/regioniveau. Duik in de details door op de stippen te klikken of