Organisatieprofiel
Introductie / missie
We use advanced microscopy techniques such as super-resolution imaging to understand the structure of synthetic nanomaterials in vitro and their biological interactions and to provide the design rules guiding the rational design of novel nanomedicines.
Vingerafdruk
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
Profielen
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Lorenzo Albertazzi
- Applied Physics and Science Education, Molecular Biosensing - Universitair Hoofddocent
- Biomedical Engineering, Nanoscopy for Nanomedicine - Universitair Hoofddocent
- ICMS Core member - Universitair Hoofddocent
Persoon: UHD : Universitair Hoofddocent
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Cristina Izquierdo Lozano
- Biomedical Engineering, Nanoscopy for Nanomedicine - Postdoc
Persoon: PD : Postdoc
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Jolien M. Marcelis
- Biomedical Engineering, Nanoscopy for Nanomedicine - Promovendus
Persoon: Prom. : Promovendus
Onderzoeksoutput
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A high-throughput approach to optimize and understand nanoparticle protein degraders
Oldenburg, J., Tholen, M. M. E., Donkers, J. G. D., Ortiz-Perez, A., Girola, V. & Albertazzi, L. (Corresponding author), 20 jan. 2026, In: Nanoscale Advances. 8, 2, blz. 479-489 11 blz.Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review
Open AccessBestand10 Downloads (Pure) -
Dissecting Nanoparticle Heterogeneity: Efficient characterization of synthetic and natural nanoparticles using super-resolution microscopy
van Veen, S. M. A., 20 jan. 2026, Eindhoven: Eindhoven University of Technology. 169 blz.Onderzoeksoutput: Scriptie › Dissertatie 1 (Onderzoek TU/e / Promotie TU/e)
Open AccessBestand -
Phenotyping by Molecular Mobility: Low-Affinity Reversible Probes Enable Characterizing and Classifying Cells Populations by Single-Molecule Imaging
Riera, R., Fitzpatrick, L. W., Huet, S., Tholen, M. M. E., Jacquot, P., Cinier, M., Woythe, L., Tanou, M., Izquierdo-Lozano, C., Verhoeven, M. & Albertazzi, L. (Corresponding author), 1 apr. 2026, In: Journal of the American Chemical Society. 148, 12, blz. 12565-12575 11 blz.Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review
Datasets
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Enabling spectrally resolved single-molecule localization microscopy at high emitter densities: Dataset
Martens, K. (Ontwerper), Gobes, M. I. (Ontwerper), Archontakis, E. (Ontwerper), Brillas, R. R. (Ontwerper), Zijlstra, N. (Ontwerper), Albertazzi, L. (Ontwerper) & Hohlbein, J. (Ontwerper), Zenodo, 29 jun. 2022
Dataset
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Glyco-PAINT-APP: Subcellular analysis of immune cell-lectin binding enables correlation of glycan binding parameters to receptor biology
Steuten, K. (Ontwerper), Bakker, J. (Ontwerper), Doelman, W. (Ontwerper), Torres-García, D. (Ontwerper), Riera Brillas, R. (Ontwerper), Albertazzi, L. (Ontwerper) & van Kasteren, S. (Ontwerper), Zenodo, 20 okt. 2025
Dataset
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Machine learning-guided high throughput nanoparticle design
Ortiz-Perez, A. (Ontwerper), van Tilborg, D. (Ontwerper), van der Meel, R. (Ontwerper), Grisoni, F. (Ontwerper) & Albertazzi, L. (Ontwerper), Zenodo, 28 aug. 2023
DOI: 10.5281/zenodo.8289605, https://zenodo.org/records/8289605
Dataset
Knipsels
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Institute for Bioengineering of Catalonia Reports Findings in Nanoparticles (A super-resolution and transmission electron microscopy correlative approach to study intracellular trafficking of nanoparticles)
1/09/23
1 item van Media-aandacht
Pers / media: Vakinhoudelijk commentaar
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Eindhoven University of Technology Reports Findings in Nanoparticles (Mapping Antibody Domain Exposure on Nanoparticle Surfaces Using DNA-PAINT)
Merkx, M., Storm, C. & Albertazzi, L.
21/06/23
1 item van Media-aandacht
Pers / media: Vakinhoudelijk commentaar
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Research Conducted at Eindhoven University of Technology Has Provided New Information about Cancer (Valency and Affinity Control of Aptamer-conjugated Nanoparticles for Selective Cancer Cell Targeting)
Albertazzi, L., van Veen, S. & Harzing, T.
11/05/23
1 item van Media-aandacht
Pers / media: Vakinhoudelijk commentaar
Impacts
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Design of cell-selective targeted nanoparticles
van Gorp, L. (Content manager)
Impact: Research Topic/Theme (at group level)
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High-throughput materials formulation and screening
van Gorp, L. (Content manager)
Impact: Research Topic/Theme (at group level)
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Super-resolution study of nanomaterials structure and properties
van Gorp, L. (Content manager)
Impact: Research Topic/Theme (at group level)
Scripties/Masterproeven
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A Modelling Approach to Nanoparticle Selective Targeting of Cancer Cells
Walker, K. R. (Auteur), van der Hofstad, R. W. (Afstudeerdocent 1) & Albertazzi, L. (Afstudeerdocent 2), jul. 2023Scriptie/Masterproef: Bachelor
Bestand -
Cell phenotyping by EGFR dynamics using a new affinity probe to perform live-cell single-particle tracking
Verhoeven, M. F. A. (Auteur), Albertazzi, L. (Afstudeerdocent 1), Merkx, M. (Afstudeerdocent 2) & Sergelen, K. (Afstudeerdocent 2), 27 jan. 2022Scriptie/Masterproef: Master
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Diffraction-unlimited imaging of heat-denatured β-lactoglobulin inside the microstructure of GDL-acidified skim milk, heated at different pH
Schnieders, L. I. (Auteur), Voets, I. K. (Afstudeerdocent 1), Albertazzi, L. (Afstudeerdocent 2), Merland, T. (Afstudeerdocent 2) & Foroutanparsa, S. (Afstudeerdocent 2), 31 aug. 2022Scriptie/Masterproef: Master