• Het Kranenveld, Helix (STO 4.33)



  • P.O. Box 513, Helix (STO 4.33)

    5600 MB Eindhoven



Introductie / missie

How far can we push chemical self-assembly? Bridging the gap between life sciences and materials science, using organic chemistry and polymer chemistry. 

Highlighted phrase

Exploration of supramolecular systems and materials

Over de organisatie

At the Macro Organic Chemistry group we educate young students to become independent scientists and make them experienced researchers in the design, synthesis, characterization and possible applications of complex molecular systems with unconventional properties. Our research addresses the challenging question “How far can we push chemical self-assembly?”. This ranges from detailed mechanistic (kinetic) investigations on the self-assembly processes of various molecular structures (e.g. the formation of ordered arrays, under thermodynamic control as well as through kinetic experiments) to the design, non-covalent synthesis and use of artificial mimics of enzymes and extracellular matrices. Our group is part of the overarching research group for Molecular Science and Technology.

From the start in 1991, our research has been focused on the design, synthesis, characterization and possible applications of new functional molecular architectures. Over the years we have worked on dendrimers, semi-conducting oligomers/polymers and several supramolecular units, with chirality as a muse. In the course of time, our focus has shifted towards the synthesis and study of complex molecular systems and in 2007 our group became the founding father of the Institute of Complex Molecular Systems (ICMS) at TU/e. More recently, a renewed interest in functional supramolecular materials for electronics and biomedical engineering has underpinned the relevance of our knowledge in the design and synthesis of molecular units that self-assemble in a controlled way, producing materials ordered at the mesoscale. 

In our current research we aim at closing the gap between organic chemistry, polymer chemistry and chemical biology by applying well-controlled supramolecular chemistry protocols. Central to this is our concept of multi-step non-covalent synthesis of molecular systems, using well-defined small and large molecules. We thus synthesize and study novel artificial molecular systems where the position of all molecules in the system can be controlled with respect to time and space. To arrive at dynamic functionalties of these molecular systems, we investigate the response to external stimuli both experimentally and theoretically.

Vingerafdruk Duik in de onderzoeksthema's waar Macro-Organic Chemistry actief is. Deze onderwerplabels komen voort uit het werk van deze leden van de organisatie. Samen vormen ze een unieke vingerafdruk.

Polymers Chemische stoffen
Self assembly Chemische stoffen
Hydrogen bonds Chemische stoffen
Molecules Chemische stoffen
Nanoparticles Chemische stoffen
Chirality Chemische stoffen
Dendrimers Chemische stoffen
Polymerization Chemische stoffen

Netwerk Recente externe samenwerking op landenniveau. Duik in de details door op de stippen te klikken.

Onderzoeksoutput 1972 2020

6 Downloads (Pure)

Architecture-dependent interplay between self-assembly and crystallization in discrete block co-oligomers

Petkau-Milroy, K., Ianiro, A., Ahn, M. M. L., Magana, J. R., Vleugels, M. E. J., Lamers, B. A. G., Tuinier, R., Voets, I. K., Palmans, A. R. A. & Meijer, E. W., 21 jan 2020, In : ACS Macro Letters. 9, 1, blz. 38-42 5 blz.

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

Open Access
Self assembly
Lactic acid
1 Downloads (Pure)

Distinct pathways in "thermally bisignate supramolecular polymerization": spectroscopic and computational studies

Rao, K. V., Mabesoone, M. F. J., Miyajima, D., Nihonyanagi, A., Meijer, E. W. & Aida, T., 8 jan 2020, In : Journal of the American Chemical Society. 142, 1, blz. 598-605 8 blz.

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

1 Downloads (Pure)

Ditopic binuclear copper(II) complexes for DNA cleavage

Carreira-Barral, I., Riopedre-Fernández, M., de Blas, A., Mosquera, J., Vázquez, M. E., Platas-Iglesias, C. & Esteban-Gómez, D., apr 2020, In : Journal of Inorganic Biochemistry. 205, April 2020, 13 blz., 110995.

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

DNA Cleavage
Methyl Green


Doctorem Honoris Causa of the Free Universitat Berlin

E.W. (Bert) Meijer (Ontvanger), 2019

Prijs: AndersHonorary degreesWetenschappelijk

NWO Veni Award : Self-oscillating surfaces

G.M.E. Vantomme (Ontvanger), 2017

Prijs: NWOVeniWetenschappelijk


NWO Vidi Award : Adaptive materials with molecular light switches

I.K. Voets (Ontvanger), 2014

Prijs: NWOVidiWetenschappelijk


Activiteiten 1992 2018

  • 10 Redactioneel werk
  • 3 Lidmaatschap van commissie
  • 2 Lidmaatschap van bestuur
  • 1 Aangemelde presentatie

Max Planck Institute for Polymer Research (Externe organisatie)

E.W. (Bert) Meijer (Lid)
2018 → …

Activiteit: Types lidmaatschapLidmaatschap van commissieWetenschappelijk

Journal of the American Chemical Society (Tijdschrift)

E.W. (Bert) Meijer (Lid redactieraad)

Activiteit: Types publicaties van collegiale toetsing en redactioneel werkRedactioneel werkWetenschappelijk

Chemical Science (Tijdschrift)

E.W. (Bert) Meijer (Lid redactieraad)

Activiteit: Types publicaties van collegiale toetsing en redactioneel werkRedactioneel werkWetenschappelijk


Light-controlled molecules: Scientists develop new recycling strategy

Fabian Eisenreich


2 items van Media-aandacht

Pers / media: Vakinhoudelijk commentaar

Discovery Could Enable Recycling of Non-Recyclable Plastics

Fabian Eisenreich


1 item van Media-aandacht

Pers / media: Vakinhoudelijk commentaar

Scientists show synthetic molecules can grow and be controlled on biological systems

E.W. (Bert) Meijer


1 item van Media-aandacht

Pers / media: Vakinhoudelijk commentaar


1,4,7-triazacyclononane functionalized BTA: a supramolecular polymer for cooperative catalysis

Auteur: Robeerst, C., 26 jun 2019

Begeleider: Mabesoone, M. (Afstudeerdocent 1), Su, L. (Afstudeerdocent 2), Meijer, B. (Afstudeerdocent 2), Palmans, A. (Afstudeerdocent 2) & Schenning, A. (Afstudeerdocent 2)

Scriptie/masterproef: Master

Bioactivation of electrospun UPy-based supramolecular polymer meshes: towards an improved treatment of pelvic floor dysfunctions

Auteur: Arts, B., 18 dec 2017

Begeleider: Dankers, P. (Afstudeerdocent 1), Zaccaria, S. (Afstudeerdocent 2) & Meijer, B. (Afstudeerdocent 2)

Scriptie/masterproef: Master

Block copolymers and crystallinity: pushing phase-separation to its limits

Auteur: Lamers, B., 22 feb 2017

Begeleider: van Genabeek, B. (Afstudeerdocent 1), Palmans, A. (Afstudeerdocent 2) & Meijer, E. (Afstudeerdocent 2)

Scriptie/masterproef: Master