!!Projects per year
Organisatieprofiel
Introductie / missie
Our mission is to make things move at small scales: fluids, particles, molecules, solid objects. We do this by carrying out research in our Microfab/lab, where we develop innovative technological concepts and microfabrication methods to create novel microfluidic devices, microactuators, and microrobotics serving a wide range of applications.
Highlighted phrase
WE MAKE THINGS WORK AT SMALL SCALES
Organisatieprofiel
In microfluidic systems, active control of fluids and species is essential. Examples are fluid pumping, mixing, mechanical actuation, sorting of cells and particles, and biomolecule capture for diagnostics. We develop and apply micro-actuators, responsive surfaces, and magnetic bead actuation systems, to realize these functions. Our approaches are often biologically inspired, translating principles from nature into technological innovations.
As an important application of our microfluidic systems, and in collaboration with biological, biomedical, and clinical groups, we develop biomedical microdevices to study and understand the behavior of cells, tissues, and organs. This work is aimed at learning about health and disease, to eventually enable the development of novel monitoring strategies, therapies and medicines. Specifically, we develop organs-on-chips as in-vitro disease models focusing on cancer, we study mechanical properties of cells, and we develop technologies for in-vitro diagnostics.
We also develop new concepts for microactuators that combine magnetic, electrical, optical and/or mechanical functionalities, for a range of applications, from microrobotics, to lithography machines to new display principles.
Vingerafdruk
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
Profielen
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Angie Carola Alarcon Rios, MSc
- Mechanical Engineering, Group Den Toonder - Postdoc
Persoon: PD : Postdoc
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projecten
- 1 Afgelopen
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Magnetic control of micro-particles and integrated micro-actuators for high precision handheld diagnostics
den Toonder, J. M. J. (Project Manager) & Shanko, E.-S. (Projectmedewerker)
1/11/16 → 31/10/20
Project: Onderzoek direct
Onderzoeksoutput
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Artificial cilia controlled modulation of biochemical microenvironments to study cellular responses
Sun, Y., 16 jun 2026, Eindhoven: Eindhoven University of Technology. 104 blz.Onderzoeksoutput: Scriptie › Dissertatie 1 (Onderzoek TU/e / Promotie TU/e)
Open AccessBestand -
Artificial embryonic node elucidates the role of flow in left-right symmetry breaking in vertebrates
ul Islam, T., Aggarwal, I., Bellouard, Y., Onck, P. R. (Corresponding author) & den Toonder, J. M. J. (Corresponding author), 27 mrt 2026, In: Science Advances. 12, 13, 11 blz., eaec2328.Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review
Open AccessBestand8 Downloads (Pure) -
Controllable Dynamic Mechanical Cell Stimulation using Magnetically Actuated Artificial Cilia
Kooi, R., Ul Islam, T., Stassen, O. M. J. A., Amsing, N., de Boer, J. & den Toonder, J. M. J. (Corresponding author), 15 mei 2026, In: Advanced Healthcare Materials. 15, 18, 15 blz., e00001.Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review
Open AccessBestand11 Downloads (Pure)
Datasets
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Source data for the publication: Curved Surfaces Induce Metachronal Motion of Microscopic Magnetic Cilia
Cui, Z. (Ontwerper), Ul Islam, T. (Ontwerper), Wang, Y. (Ontwerper) & den Toonder, J. M. J. (Ontwerper), 4TU.Centre for Research Data, 15 nov 2024
DOI: 10.4121/49513019-dc6d-4f6e-9bc5-36bc4d8db1a7, https://data.4tu.nl/datasets/49513019-dc6d-4f6e-9bc5-36bc4d8db1a7 en nog één link, https://data.4tu.nl/datasets/49513019-dc6d-4f6e-9bc5-36bc4d8db1a7/1 (minder tonen)
Dataset
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Source data for the publication: Enhancement of microalgae growth using magnetic artificial cilia
Verburg, T. H. C. M. (Ontwerper), Schaap, A. (Ontwerper), Zhang, S. (Ontwerper), den Toonder, J. (Ontwerper) & Wang, Y. (Ontwerper), 4TU.Centre for Research Data, 15 nov 2024
DOI: 10.4121/90b75bcc-fe98-4c92-bfd1-97d1801d2cdc, https://data.4tu.nl/datasets/90b75bcc-fe98-4c92-bfd1-97d1801d2cdc en nog één link, https://data.4tu.nl/datasets/90b75bcc-fe98-4c92-bfd1-97d1801d2cdc/1 (minder tonen)
Dataset
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Source data for the publication: A Cell Pre-Wrapping Seeding Technique for Hydrogel-Based Tubular Organ-On-A-Chip
Nie, J. (Ontwerper), Lou, S. (Ontwerper), Pollet, A. (Ontwerper), van Vegchel, M. (Ontwerper), Bouten, C. V. C. (Ontwerper) & den Toonder, J. M. J. (Ontwerper), 4TU.Centre for Research Data, 15 nov. 2024
DOI: 10.4121/6b6afa04-cf9c-4273-8150-8eb34c22b138, https://data.4tu.nl/datasets/6b6afa04-cf9c-4273-8150-8eb34c22b138 en nog één link, https://data.4tu.nl/datasets/6b6afa04-cf9c-4273-8150-8eb34c22b138/1 (minder tonen)
Dataset
Prijzen
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Famelab Heat 2021(Audience's choice award)
Jouy Bar, M. (Ontvanger), 29 apr. 2021
Prijs: Anders › Werk, activiteit of publicatie gerelateerde prijzen (lifetime, best paper, poster etc.) › Wetenschappelijk
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FameLab National Final 2021
Jouy Bar, M. (Ontvanger), 1 jun. 2021
Prijs: Anders › Werk, activiteit of publicatie gerelateerde prijzen (lifetime, best paper, poster etc.) › Wetenschappelijk
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Netherlands Academy of Engineering Fellow
den Toonder, J. M. J. (Ontvanger), 2023
Prijs: Anders › Fellowships & memberships › Wetenschappelijk
Activiteiten
- 6 Redactioneel werk
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Bio-Design and Manufacturing (Tijdschrift)
den Toonder, J. M. J. (Lid redactieraad)
2024 → …Activiteit: Types publicaties van collegiale toetsing en redactioneel werk › Redactioneel werk › Wetenschappelijk
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Micromachines (Tijdschrift)
den Toonder, J. M. J. (Lid redactieraad)
2018 → …Activiteit: Types publicaties van collegiale toetsing en redactioneel werk › Redactioneel werk › Wetenschappelijk
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Biomicrofluidics (Tijdschrift)
den Toonder, J. M. J. (Lid redactieraad)
2018 → …Activiteit: Types publicaties van collegiale toetsing en redactioneel werk › Redactioneel werk › Wetenschappelijk
Knipsels
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GLOBAL ROUND UP SECTOR WEEKLY: UNIVERSITY NEWSLETTER OF WEEK-ENDED NOV 05, 2023
Baaijens, F. P. T., Steinbuch, M., Mulder, W. J. M., den Toonder, J. M. J. & Lüttge, R.
6/11/23
1 item van Media-aandacht
Pers / media: Vakinhoudelijk commentaar
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Six TU/e researchers appointed fellows of the new Netherlands Academy of Engineering
Baaijens, F. P. T., Steinbuch, M., Mulder, W. J. M., den Toonder, J. M. J., Lüttge, R. & Fitzgerald, B.
2/11/23 → 3/11/23
2 items van Media-aandacht
Pers / media: Vakinhoudelijk commentaar
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Reports from Xi'an University of Technology Advance Knowledge in Ecology, Environment and Conservation (Hydrochemical Assessments and Driving Forces of Water Resources In Coal Mining Areas: a Case Study of the Changhe River Basin, Shanxi)
20/10/23
1 item van Media-aandacht
Pers / media: Vakinhoudelijk commentaar
Scripties/Masterproeven
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A microfluidic platform for multiplexed continuous monitoring using bioluminescent immunoassays
Jansen, T. P. A. (Auteur), Rosier, B. J. H. M. (Afstudeerdocent 1), van Aalen, E. A. (Afstudeerdocent 2) & Merkx, M. (Afstudeerdocent 2), 31 aug 2023Scriptie/Masterproef: Master
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Analysis of liquid crystal actuation towards a light-driven amphibious soft microrobot
van Beek, J. C. (Auteur), den Toonder, J. M. J. (Afstudeerdocent 1), Schenning, A. P. H. J. (Afstudeerdocent 2), Pilz Da Cunha, M. (Afstudeerdocent 2) & Wang, Y. (Afstudeerdocent 2), 19 jan 2021Scriptie/Masterproef: Master
Bestand -
An integrated approach to study the aerotaxis of breast cancer cells in a 3D environment using an oxygen diffusion chip
Selhorst, L. (Auteur), Sleeboom, J. J. F. (Afstudeerdocent 1) & Sahlgren, C. M. (Afstudeerdocent 2), 27 aug 2020Scriptie/Masterproef: Master