Projecten per jaar
Organisatieprofiel
Introductie / missie
Our mission is to make things move at small scales: fluids, particles, molecules, solid structures. We do this by carrying out research in our Microfab/lab, where we develop innovative technological concepts and fabrication methods to create novel microfluidic devices and microactuators, serving a wide range of applications.
Highlighted phrase
We make things move at small scales!
Organisatieprofiel
In microfluidic systems, active control of fluids and species is essential. Examples are fluid pumping, mixing, mechanical actuation, sorting of cells and particles, and biomolecule capture for diagnostics. We develop and apply micro-actuators, responsive surfaces, and magnetic bead actuation systems, to realize these functions. Our approaches are often biologically inspired, translating principles from nature into technological innovations.
As an important application of our microfluidic systems, and in collaboration with biological, biomedical, and clinical groups, we develop biomedical microdevices to study and understand the behavior of cells, tissues, and organs. This work is aimed at learning about health and disease, and eventually developing novel therapies and medicines. Specifically, we develop organs-on-chips as in-vitro disease models focusing on cancer, we study mechanical properties of single cells, and we develop technologies for in-vitro diagnostics. In addition, we develop biomedical devices that can be applied to treat patients non-invasively, such as a glaucoma eye implant.
We also develop new concepts for microactuators that combine electrical, optical and/or mechanical functionalities, for other applications, from lithography machines to new display principles to air quality monitoring to microrobotics.
Vingerafdruk
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
Profielen
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Angie Carola Alarcon Rios, MSc
- Mechanical Engineering, Group Den Toonder - Postdoc
Persoon: PD : Postdoc
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Jan-Willem M. van Bree
- Mechanical Engineering, Group Den Toonder - Research Fellow
Persoon: OWP : Docent / Onderzoeker
projecten
- 1 Afgelopen
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Magnetic control of micro-particles and integrated micro-actuators for high precision handheld diagnostics
den Toonder, J. M. J. (Project Manager) & Shanko, E. (Projectmedewerker)
1/11/16 → 31/10/20
Project: Onderzoek direct
Onderzoeksoutput
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All Organic Fully Integrated Neuromorphic Crossbar Array
Kazemzadeh, S., Stevens, T. & van de Burgt, Y. (Corresponding author), 22 feb. 2025, (E-publicatie vóór gedrukte publicatie) In: Advanced Electronic Materials. XX, X, 2500054.Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review
Open Access -
A novel kinetic model estimating the urea concentration in plasma during non-invasive sweat-based monitoring in hemodialysis
Yin, X. (Corresponding author), Adelaars, S., Peri, E., Pelssers, E., den Toonder, J. M. J., Bouwman, R. A., van de Kerkhof, D. H. & Mischi, M., 18 mrt. 2025, In: Frontiers in Physiology. 16, 12 blz., 1547117.Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review
Open AccessBestand4 Downloads (Pure) -
A personalized model and optimization strategy for estimating blood glucose concentrations from sweat measurements
Yin, X. (Corresponding author), Peri, E., Pelssers, E., den Toonder, J. M. J., Klous, L., Daanen, H. & Mischi, M., jun. 2025, In: Computer Methods and Programs in Biomedicine. 265, 11 blz., 108743.Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review
Open AccessBestand1 Citaat (Scopus)18 Downloads (Pure)
Datasets
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Source data for the publication: Curved Surfaces Induce Metachronal Motion of Microscopic Magnetic Cilia
Cui, Z. (Ontwerper), Ul Islam, T. (Ontwerper), Wang, Y. (Ontwerper) & den Toonder, J. M. J. (Ontwerper), 4TU.Centre for Research Data, 15 nov. 2024
DOI: 10.4121/49513019-dc6d-4f6e-9bc5-36bc4d8db1a7, https://data.4tu.nl/datasets/49513019-dc6d-4f6e-9bc5-36bc4d8db1a7 en nog één link, https://data.4tu.nl/datasets/49513019-dc6d-4f6e-9bc5-36bc4d8db1a7/1 (minder tonen)
Dataset
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Source data for the publication: Enhancement of microalgae growth using magnetic artificial cilia
Verburg, T. H. C. M. (Ontwerper), Schaap, A. (Ontwerper), Zhang, S. (Ontwerper), den Toonder, J. (Ontwerper) & Wang, Y. (Ontwerper), 4TU.Centre for Research Data, 15 nov. 2024
DOI: 10.4121/90b75bcc-fe98-4c92-bfd1-97d1801d2cdc, https://data.4tu.nl/datasets/90b75bcc-fe98-4c92-bfd1-97d1801d2cdc en nog één link, https://data.4tu.nl/datasets/90b75bcc-fe98-4c92-bfd1-97d1801d2cdc/1 (minder tonen)
Dataset
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Source data for the publication: A Cell Pre-Wrapping Seeding Technique for Hydrogel-Based Tubular Organ-On-A-Chip
Nie, J. (Ontwerper), Lou, S. (Ontwerper), Pollet, A. (Ontwerper), van Vegchel, M. (Ontwerper), Bouten, C. V. C. (Ontwerper) & den Toonder, J. M. J. (Ontwerper), 4TU.Centre for Research Data, 15 nov. 2024
DOI: 10.4121/6b6afa04-cf9c-4273-8150-8eb34c22b138, https://data.4tu.nl/datasets/6b6afa04-cf9c-4273-8150-8eb34c22b138 en nog één link, https://data.4tu.nl/datasets/6b6afa04-cf9c-4273-8150-8eb34c22b138/1 (minder tonen)
Dataset
Prijzen
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Famelab Heat 2021(Audience's choice award)
Jouy Bar, M. (Ontvanger), 29 apr. 2021
Prijs: Anders › Werk, activiteit of publicatie gerelateerde prijzen (lifetime, best paper, poster etc.) › Wetenschappelijk
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FameLab National Final 2021
Jouy Bar, M. (Ontvanger), 1 jun. 2021
Prijs: Anders › Werk, activiteit of publicatie gerelateerde prijzen (lifetime, best paper, poster etc.) › Wetenschappelijk
Knipsels
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Six TU/e researchers appointed fellows of the new Netherlands Academy of Engineering
Baaijens, F. P. T., Steinbuch, M., Mulder, W. J. M., den Toonder, J. M. J., Lüttge, R. & Fitzgerald, B.
2/11/23 → 3/11/23
2 items van Media-aandacht
Pers / media: Vakinhoudelijk commentaar
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Engineers create artificial cilia at the microscale
13/09/23
2 items van Media-aandacht
Pers / media: Vakinhoudelijk commentaar
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New Findings from Eindhoven University of Technology in the Area of Science Published (Miniaturized metachronal magnetic artificial cilia)
Wang, T., Cui, Z., den Toonder, J. M. J. & Wang, Y.
7/09/23
1 item van Media-aandacht
Pers / media: Vakinhoudelijk commentaar
Scripties/Masterproeven
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A microfluidic platform for multiplexed continuous monitoring using bioluminescent immunoassays
Jansen, T. P. A. (Auteur), Rosier, B. J. H. M. (Afstudeerdocent 1), van Aalen, E. A. (Afstudeerdocent 2) & Merkx, M. (Afstudeerdocent 2), 31 aug. 2023Scriptie/Masterproef: Master
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Analysis of liquid crystal actuation towards a light-driven amphibious soft microrobot
van Beek, J. C. (Auteur), den Toonder, J. M. J. (Afstudeerdocent 1), Schenning, A. P. H. J. (Afstudeerdocent 2), Pilz Da Cunha, M. (Afstudeerdocent 2) & Wang, Y. (Afstudeerdocent 2), 19 jan. 2021Scriptie/Masterproef: Master
Bestand -
An integrated approach to study the aerotaxis of breast cancer cells in a 3D environment using an oxygen diffusion chip
Selhorst, L. (Auteur), Sleeboom, J. J. F. (Afstudeerdocent 1) & Sahlgren, C. M. (Afstudeerdocent 2), 27 aug. 2020Scriptie/Masterproef: Master