Projecten per jaar
Organisatieprofiel
Introductie / missie
Our mission is to make things move at small scales: fluids, particles, molecules, solid structures. We do this by carrying out research in our Microfab/lab, where we develop innovative technological concepts and fabrication methods to create novel microfluidic devices and microactuators, serving a wide range of applications.
Highlighted phrase
We make things move at small scales!
Over de organisatie
In microfluidic systems, active control of fluids and species is essential. Examples are fluid pumping, mixing, mechanical actuation, sorting of cells and particles, and biomolecule capture for diagnostics. We develop and apply micro-actuators, responsive surfaces, and magnetic bead actuation systems, to realize these functions. Our approaches are often biologically inspired, translating principles from nature into technological innovations.
As an important application of our microfluidic systems, and in collaboration with biological, biomedical, and clinical groups, we develop biomedical microdevices to study and understand the behavior of cells, tissues, and organs. This work is aimed at learning about health and disease, and eventually developing novel therapies and medicines. Specifically, we develop organs-on-chips as in-vitro disease models focusing on cancer, we study mechanical properties of single cells, and we develop technologies for in-vitro diagnostics. In addition, we develop biomedical devices that can be applied to treat patients non-invasively, such as a glaucoma eye implant.
We also develop new concepts for microactuators that combine electrical, optical and/or mechanical functionalities, for other applications, from lithography machines to new display principles to air quality monitoring to microrobotics.
Vingerafdruk
Netwerk
Profielen
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Eva A. van Aalen
- Biomedical Engineering, Protein Engineering - Promovendus
- Mechanical Engineering, Microsystems - Promovendus
- Mechanical Engineering, Group Den Toonder - Promovendus
Persoon: Prom. : Promovendus
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Liesbeth van Ballegooij
- Mechanical Engineering, Group Den Toonder - Secretaresse
- Mechanical Engineering, Microsystems - Secretaresse
Persoon: Secr. : Secretaresse
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Zhiwei Cui
- Mechanical Engineering, Microsystems - Promovendus
- Mechanical Engineering, Group Den Toonder - Promovendus
Persoon: Prom. : Promovendus
projecten
- 1 Afgelopen
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Magnetic control of micro-particles and integrated micro-actuators for high precision handheld diagnostics
den Toonder, J. M. J. & Shanko, E.
1/11/16 → 31/10/20
Project: Onderzoek direct
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Acoustic characterization of tissue-mimicking materials for ultrasound perfusion imaging research
Chen, P., Pollet, A. M. A. O., Panfilova, A., Zhou, M., Turco, S., den Toonder, J. M. J. & Mischi, M., jan. 2022, In: Ultrasound in Medicine and Biology. 48, 1, blz. 124-142 19 blz.Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review
Open AccessBestand2 Citaten (Scopus)43 Downloads (Pure) -
An integrated system for automated measurement of airborne pollen based on electrostatic enrichment and image analysis with machine vision
Yang, J. J., Klinkenberg, C., Pan, J-Z., Wyss, H. M., den Toonder, J. M. J. & Fang, Q., 15 jan. 2022, In: Talanta. 237, 9 blz., 122908.Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review
Open AccessBestand1 Downloads (Pure) -
A Prototype System with Custom-Designed RX ICs for Contrast-Enhanced Ultrasound Imaging
Zhou, M., Chen, P., Pollet, A. M. A. O., Ouzounov, S., den Toonder, J. M. J., Mischi, M., Cantatore, E. & Harpe, P., 1 mei 2022, In: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 69, 5, blz. 1649-1660 12 blz.Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review
Prijzen
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Famelab Heat 2021(Audience's choice award)
Jouy Bar, Mohammad (Ontvanger), 29 apr. 2021
Prijs: Anders › Werk, activiteit of publicatie gerelateerde prijzen (lifetime, best paper, poster etc.) › Wetenschappelijk
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FameLab National Final 2021
Jouy Bar, Mohammad (Ontvanger), 1 jun. 2021
Prijs: Anders › Werk, activiteit of publicatie gerelateerde prijzen (lifetime, best paper, poster etc.) › Wetenschappelijk
Knipsels
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Changchun Inst Optics Fine Mech & Physics, CAS Seeks Patent for Method for Calculating Surface Shape of Optical Mirror Surface
Ye Wang & Yue Wang
25/04/22
2 items van Media-aandacht
Pers / media: Vakinhoudelijk commentaar
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Features Pivot Park and Brainport have to get off their islands, but how?
19/04/22
1 item van Media-aandacht
Pers / media: Vakinhoudelijk commentaar
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Sweet way to study blood vessels near tumors 4 April
Massimo Mischi, Jaap M.J. den Toonder, Andreas Pollet, Meiyi Zhou & Peiran Chen
4/04/22
2 items van Media-aandacht
Pers / media: Vakinhoudelijk commentaar
Scripties/Masterproeven
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Analysis of liquid crystal actuation towards a light-driven amphibious soft microrobot
Auteur: van Beek, J. C., 19 jan. 2021Begeleider: den Toonder, J. M. J. (Afstudeerdocent 1), Schenning, A. P. H. J. (Afstudeerdocent 2), Pilz Da Cunha, M. (Afstudeerdocent 2) & Wang, Y. (Afstudeerdocent 2)
Scriptie/Masterproef: Master
Bestand -
An integrated approach to study the aerotaxis of breast cancer cells in a 3D environment using an oxygen diffusion chip
Auteur: Selhorst, L., 27 aug. 2020Begeleider: Sleeboom, J. J. F. (Afstudeerdocent 1) & Sahlgren, C. M. (Afstudeerdocent 2)
Scriptie/Masterproef: Master
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Bioluminescent dCas9 sensor for sensitive and sequence-specific nucleic acid detection
Auteur: van der Veer-Agema, H. J., 11 okt. 2021Begeleider: van Aalen, E. A. (Afstudeerdocent 1) & Merkx, M. (Afstudeerdocent 2)
Scriptie/Masterproef: Master