Projecten per jaar
Organisatieprofiel
Introductie / missie
Constructing computational models to improve the knowledge of diseases, biomedical processes and structures.
Highlighted phrase
Describing, understanding and ultimately controlling life's processes
Over de organisatie
The research group Computational Biology develops computational models that help to obtain qualitative and quantitative knowledge of diseases, biomedical processes and structures. The computational models are developed based on a thorough understanding of molecular modeling methods, data analysis techniques, machine learning, systems biology, and parameter estimation techniques. Next to data obtained through collaborations and partnerships with other university groups, companies and hospitals, within the Synthetic Biology arena data is also achieved by own experiments. Topics of research are, amongst others, biomembranes, protein interactions, complex biochemical networks, and diseases like metabolic syndrome, diabetes mellitus and cancer. The group also puts efforts in enhancing the shift from ‘describing’ life’s processes to ‘understanding’ them and ‘capturing’ them in validated predictive models, and even ‘managing’ or ‘controlling’ them in real life. Research themes of the group are Molecular Simulations, Systems Biology and Metabolic Disease, Systems Biology for Oncology, Synthetic Biology, Data Science and Bioinformatics.
Vingerafdruk
Netwerk
Profielen
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Mart Bartelds, MSc
- Biomedical Engineering, Computational Biology - Onderzoeker
- Biomedical Engineering, Synthetic Biology - Onderzoeker
Persoon: OWP : Docent / Onderzoeker
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Bas Bögels
- Biomedical Engineering, Computational Biology - Promovendus
- Biomedical Engineering, Chemical Biology - Promovendus
- Biomedical Engineering, Synthetic Biology - Promovendus
Persoon: Prom. : Promovendus
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Dragan Bosnacki
- Biomedical Engineering, Systems Biology and Metabolic Disease - Universitair Docent
- Biomedical Engineering, Computational Biology - Universitair Docent
- EAISI Health - Universitair Docent
Persoon: UD : Universitair Docent
projecten
- 1 Actief
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NWO/Complexity/MATRyOSka
van Riel, N. A. W., O'Donovan, S., Arts, I. C. W. & Afman, L.
1/10/17 → 31/12/22
Project: Onderzoek direct
Onderzoeksoutput
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Accuracy of vital parameters measured by a wearable patch following major abdominal cancer surgery
van der Stam, J. A., Mestrom, E. H. J., Scheerhoorn, J., Jacobs, F., de Hingh, I. H. J. T., van Riel, N. A. W., Boer, A-K., Scharnhorst, V., Nienhuijs, S. W. & Bouwman, R. A., apr. 2022, In: European Journal of Surgical Oncology. 48, 4, blz. 917-923 7 blz.Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review
Open AccessBestand2 Downloads (Pure) -
A Markov model for inferring event types on diabetes patients data
Ferreira de Carvalho, D., Kaymak, U., Van Gorp, P. & van Riel, N., 1 nov. 2022, In: Healthcare Analytics. 2, 10 blz., 100024.Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review
Open AccessBestand3 Downloads (Pure) -
DNA Input Classification by a Riboregulator-Based Cell-Free Perceptron
van der Linden, A. J., Pieters, P. A., Bartelds, M. W., Nathalia, B. L., Yin, P., Huck, W. T. S., Kim, J. & de Greef, T. F. A., 15 apr. 2022, In: ACS Synthetic Biology. 11, 4, blz. 1510-1520 11 blz.Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review
Open AccessBestand8 Downloads (Pure)
Prijzen
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AMC Principal Investigator
van Riel, Natal A.W. (Ontvanger), 1 mei 2016
Prijs: Anders › Werk, activiteit of publicatie gerelateerde prijzen (lifetime, best paper, poster etc.) › Wetenschappelijk
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Best poster award
Rozendaal, Y. (Ontvanger), 28 okt. 2016
Prijs: Anders › Werk, activiteit of publicatie gerelateerde prijzen (lifetime, best paper, poster etc.) › Wetenschappelijk
Activiteiten
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Personalized modelling of bile acid metabolism: predicting metabolic effects of bariatric surgery
Natal van Riel (Spreker)
6 jul. 2018Activiteit: Types gesprekken of presentaties › Genodigd spreker › Wetenschappelijk
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A physiology based glucose-insulin-GLP-1 model: explaining changes observed after Roux-en-Y gastric bypass
L.C.P. Thijssen (Spreker) & Natal van Riel (Deelnemer)
15 mei 2018Activiteit: Types gesprekken of presentaties › Aangemelde presentatie › Wetenschappelijk
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4th Dutch Bioinformatics & Systems Biology Conference
Natal van Riel (Organisator)
15 mei 2018 → 16 mei 2018Activiteit: Types deelname aan of organisatie van een evenement › Congres › Wetenschappelijk
Knipsels
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Technische Universiteit Eindhoven awarded contract for Flow Cytometer
26/07/21
1 item van Media-aandacht
Pers / media: Vakinhoudelijk commentaar
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Using Machine Learning Methods to Predict Response to Immunotherapy
1/07/21
1 item van Media-aandacht
Pers / media: Vakinhoudelijk commentaar
Impacts
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Bioinformatics and Mathematical Modelling
Rina van Dijck-Postma (Content manager), Sylvia van Beek-Verschure (Content manager), Lieke van Gorp (Content manager) & Amy Broeders (Content manager)
Impact: Research Topic/Theme (at group level)
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Brain Image Analysis
Josien P.W. Pluim (Content manager), Sylvia van Beek-Verschure (Content manager), Lieke van Gorp (Content manager), Amy Broeders (Content manager) & Erica Jansen (Content manager)
Impact: Research Topic/Theme (at group level)
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Cardiovascular Image Analysis
Josien P.W. Pluim (Content manager), Sylvia van Beek-Verschure (Content manager), Lieke van Gorp (Content manager), Amy Broeders (Content manager) & Erica Jansen (Content manager)
Impact: Research Topic/Theme (at group level)
Scripties/Masterproeven
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A computational biology framework: a data analysis tool to support biomedical engineers in their research
Auteur: Beishuizen, T. P. A., 29 nov. 2018Begeleider: Bosnacki, D. (Afstudeerdocent 1), Cheplygina, V. (Afstudeerdocent 2), Hilbers, P. A. J. (Afstudeerdocent 2), Fletcher, G. (Afstudeerdocent 2) & Vanschoren, J. (Afstudeerdocent 2)
Scriptie/Masterproef: Master
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An object-oriented framework to model glucose and insulin dynamics
Auteur: Bossink, R. P. G., 14 jun. 2021Begeleider: Hilbers, P. A. J. (Afstudeerdocent 1) & van Riel, N. A. W. (Afstudeerdocent 2)
Scriptie/Masterproef: Master
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A physiology based glucose-insulin-GLP-1 model: explaining changes observed after Roux-en-Y gastric bypass
Auteur: Thijssen, L. C. P., 30 aug. 2018Begeleider: Sips, F. (Afstudeerdocent 1), Yildirim, V. (Afstudeerdocent 2), van Riel, N. (Afstudeerdocent 2) & Hilbers, P. A. J. (Afstudeerdocent 2)
Scriptie/Masterproef: Master