• Groene Loper 15, Gemini-Zuid 3.115

    5612 AZ Eindhoven

    Nederland

Organisatieprofiel

Introductie / missie

MRI and MRS offer exciting possibilities for the investigation of a range of structural, functional and metabolic parameters in living systems.

MRI and MRS are non-invasive and therefore ideally suited for repeated studies, in which changes in tissues are followed over time. This non-invasiveness and the richness of the information that is obtained explain the important role of MR in biological and biomedical research. Not surprisingly, MR has also rapidly gained an important position in human healthcare since its first arrival in medical centers in the late 1980’s.

Highlighted phrase

The research and teaching program of the BioMedical NMR group is aimed at the development and use of in vivo magnetic resonance imaging (MRI) and spectroscopy (MRS) techniques. 

Over de organisatie

The central aim of our research program is to push the limits of biomedical MR. New techniques are developed and validated by studies on biological preparations in vitro and animal models in vivo, and where possible applied in clinical human research. The technology developments in our group are inspired by important biomedical and healthcare problems:

  1. skeletal muscle disorders, especially type 2 diabetes and decubitus;
  2. cardiovascular disorders, including atherosclerosis and cardiac infarction;
  3. molecular imaging of disease biomarkers and the development of target-specific contrast agents.

These themes were chosen because:

  1. diseases of skeletal muscle and the cardiovascular system have a major socio-economic impact;
  2. MR has the potential to greatly improve the diagnosis and management of these disorders;
  3. novel MRI protocols combined with targeted contrast agents can strongly enhance the specificity and sensitivity of diagnostic MRI.

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Profielen

Geen foto van Ot Bakermans
20112015
Foto van Holger Grüll
20072019
Geen foto van Jules L. Nelissen
20142019

Onderzoeksoutput 1978 2019

Correction to: imaging of tumor spheroids, dual-isotope SPECT, and autoradiographic analysis to assess the tumor uptake and distribution of different nanobodies

Beltrán Hernández, I., Rompen, R., Rossin, R., Xenaki, K. T., Katrukha, E. A., Nicolay, K., Henegouwen, P. V. B. E., Grüll, H. & Oliveira, S., 15 apr 2019, In : Molecular Imaging and Biology. 1 blz.

Onderzoeksoutput: Bijdrage aan tijdschriftCommentaar/Brief aan de redacteurAcademicpeer review

Open Access
Single-Domain Antibodies
Single-Photon Emission-Computed Tomography
Isotopes
Neoplasms

Dynamics in human muscle bioenergetics: in silico and in vivo studies of metabolism during exercise

Hendriks, A., Nabben, M. W., Schmitz, J. P. J., Hilbers, P. A. J., Prompers, J. J. & van Riel, N. A. W., 2019, (In voorbereiding) Eindhoven: Technische Universiteit Eindhoven

Onderzoeksoutput: WerkdocumentAcademic

1 Citaat (Scopus)

Imaging of tumor spheroids, dual-isotope SPECT, and autoradiographic analysis to assess the tumor uptake and distribution of different nanobodies

Beltrán Hernández, I., Rompen, R., Rossin, R., Xenaki, K. T., Katrukha, E. A., Nicolay, K., van Bergen en Henegouwen, P., Grüll, H. & Oliveira, S., 11 mrt 2019, In : Molecular Imaging and Biology.

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

Open Access
Single-Domain Antibodies
Single-Photon Emission-Computed Tomography
Isotopes
Neoplasms
Autoradiography

Prijzen

NWO Veni Award : Changes in the failing heart

M.W. Nabben (Ontvanger), 2013

Prijs: NWOVeniWetenschappelijk

Heart Diseases
Heart Failure
Research Personnel
Therapeutics

Pers/media

Nanotechnology-Based Immunotherapy that Promotes Organ Transplant Acceptance

Gustav Strijkers

7/11/18

1 item van media-aandacht

Pers / media: Vakinhoudelijk commentaar

Skull Surprise

Katrien Vandoorne

30/08/18

1 item van media-aandacht

Pers / media: Vakinhoudelijk commentaar

Scientists discover channels in the skull that may provide a shortcut for immune cells

Katrien Vandoorne

30/08/18

1 item van media-aandacht

Pers / media: Vakinhoudelijk commentaar

Scripties/masterproeven

Cerebral activation reflects loudness perception rather than physical sound intensity: an fMRI study in normally hearing and hearing-impaired subjects

Auteur: Schoenmaker, E., 28 feb 2005

Begeleider: Langers, D. (Afstudeerdocent 1), Backes, W. (Afstudeerdocent 2), van Dijk, P. (Afstudeerdocent 2), Manni, J. (Externe persoon) (Afstudeerdocent 2), van Engelshoven, J. M. (Afstudeerdocent 2) & Nicolay, K. (Afstudeerdocent 2)

Scriptie/masterproef: Master

Development of protein-liposome conjugates using native chemical ligation

Auteur: Brusselaars, W., 2007

Begeleider: Reulen, S. (Afstudeerdocent 1), Merkx, M. (Afstudeerdocent 2), Meijer, B. (Afstudeerdocent 2), Sommerdijk, N. (Afstudeerdocent 2) & Nicolaij, K. (Afstudeerdocent 2)

Scriptie/masterproef: Master

Machnetic resonance neurograpy of the celiac plexus with motion-compensated 3D SHINKEI

Auteur: Kok, L., 20 jun 2017

Begeleider: Strijkers, G. (Afstudeerdocent 1), Ferrer, C. (Externe persoon) (Externe coach), Bos, C. (Externe persoon) (Externe coach), van Leeuwen, M. (Externe persoon) (Externe coach) & Lopata, R. (Afstudeerdocent 2)

Scriptie/masterproef: Master