Biomedical Materials and Chemistry

  • Institute for Complex Molecular Systems Department of Biomedical Engineering, P.O. Box 513

    5600 MB Eindhoven

    Nederland

Organisatieprofiel

Introductie / missie

To provide material solutions for regenerative medicine through development of functional biomaterials based on supramolecular chemistry.

Highlighted phrase

The Biomaterials research group focusses on the design and synthesis of bioinspired functional biomaterials.

Over de organisatie

The Biomaterials research group focusses on the design and synthesis of bioinspired functional biomaterials. The main goals are: 1. To develop methods to specifically modify biomaterials surfaces, and 2. To translate these biomaterials to applications in the field of regenerative medicine, with a focus on cardiovascular and renal applications.

The biomedical application of different supramolecular polymeric biomaterials held together via directed, non-covalent interactions is the central theme. In the cardiovascular field the aim is to develop vascular grafts and heart valves that in situ can be engineered by selective capturing of progenitor cells from the blood (in close collaboration with prof. Carlijn Bouten). Additionally, catheter-delivery methods of various drugs, cells and exosomes, encapsulated in hydrogels, to the heart after myocardial infarction are investigated. Furthermore, the Biomaterials research group also designs and develops biomaterials to intervene in processes related to kidney disease. In order to ameliorate hemodialysis bilayered supramolecular membranes on which kidney cells can be cultured outside the body are developed.

Vingerafdruk Duik in de onderzoeksthema's waar Biomedical Materials and Chemistry actief is. Deze onderwerplabels komen voort uit het werk van deze leden van de organisatie. Samen vormen ze een unieke vingerafdruk.

Pyrimidinones Chemische stoffen
Hydrogels Engineering en materiaalwetenschappen
Biocompatible Materials Chemische stoffen
Biomaterials Engineering en materiaalwetenschappen
Hydrogel Chemische stoffen
Peptides Engineering en materiaalwetenschappen
Scaffolds Chemische stoffen
Bone Chemische stoffen

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Onderzoeksoutput 2016 2019

  • 28 Tijdschriftartikel
  • 9 Dissertatie 1 (Onderzoek TU/e / Promotie TU/e)
  • 1 Hoofdstuk
  • 1 Editorial
5 Downloads (Pure)

A supramolecular platform for the introduction of Fc-fusion bioactive proteins on biomaterial surfaces

Sahlgren, C. M., de Jong, S. M. J., Stassen, O. M. J. A., Sahlgren, C. M. & Dankers, P. Y. W., 9 aug 2019, In : ACS Applied Polymer Materials. 1, 8, blz. 2044-2054 11 blz.

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

Open Access
Bestand
Biocompatible Materials
Pyrimidinones
Proteins
Notch1 Receptor
Click Chemistry
9 Citaties (Scopus)
18 Downloads (Pure)

Carbon nanotube reinforced supramolecular hydrogels for bioapplications

Mihajlovic, M., Mihajlovic, M., Dankers, P. Y. W., Masereeuw, R. & Sijbesma, R. P., 1 jan 2019, In : Macromolecular Bioscience. 19, 12 blz., 1800173.

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

Open Access
Bestand
Carbon Nanotubes
Hydrogels
Nanocomposites
Carbon nanotubes
Hydrogel
Open Access
antifouling
Biocompatible Materials
Biomaterials
Peptides
peptides

Prijzen

NWO Vidi Award : Pieces of plastic with biological properties?

P.Y.W. Dankers (Ontvanger), 2016

Prijs: NWOVidiWetenschappelijk

Bearings (structural)
Tissue
Plastics
Polymers
Supramolecular chemistry
Biocompatible Materials
Medicine
Tissue
Medical problems

Supramolecular hydrogels as local controlled drug delivery carriers

P.Y.W. Dankers (Ontvanger), 2016

Prijs: ERCProof of conceptWetenschappelijk

Drug Carriers
Hydrogels
Hydrogel
Pyrimidinones
Drug Delivery Systems

Scripties/masterproeven

Introduction of Notch ligands at the surface of supramolecular biomaterials

Auteur: de Jong, S., 23 mei 2019

Begeleider: Putti, M. (Afstudeerdocent 1) & Dankers, P. (Afstudeerdocent 2)

Scriptie/masterproef: Master

Renal epithelial sheet response to curved surfaces

Auteur: Miltenburg, R., 30 aug 2018

Begeleider: van Gaal, R. (Afstudeerdocent 1) & Dankers, P. (Afstudeerdocent 2)

Scriptie/masterproef: Master