Macro Organic Chemistry

URL study guide

https://tue.osiris-student.nl/onderwijscatalogus/extern/cursus?cursuscode=6BER02&collegejaar=2025&taal=en

Omschrijving

The course teaches student the Molecular Language, Carbohydrate Chemistry, Natural and Synthetic polymers, Aromatic Substitutions, Coupling Reactions and Retrosynthesis, Condensation Reactions and Retrosynthesis, Pericyclic Reactions and Retrosynthesis, and Heterocyclic Compounds and Retrosynthesis.

Extra information about entry requirements:
Course that has to be completed to register for this course:
For CE&C Students:
Introduction to Molecules and Processes (6BBR01)
Organic Chemistry 1 (6BMR01)
For BMT students:
Introduction Organic Chemistry (8BA010)

Extra information about the assessment
For this course, there will be one interim assessment (not obligatory) via formative multiple choice questions on the content of the first 3 weeks; Passing this test will allow to gain a bonus that is added to the mark of the final exam (0.5 or 1.0 bonus point depending on the grade) to be added to the mark of the final exam. The results of mid-term assessment moments and final tests are only valid in the academic year in which the mid-term assessment moments and final tests were taken.

Doelstellingen

• The student is able to recognise nucleophilic and electrophilic centers in organic molecules. 
• The student is able to connect electronic structure, resonance, aromaticity, electronegativity and acidity to the reactivity of the molecule.
• The student is able to recognise stereochemical elements in molecules and assign configurations according to the CIP nomenclature.
• The student is able to draw reaction mechanisms for the reactions dealt with in the course.
• The student is able to distinguish between substitution, addition, elemination and pericyclic reactions and knows which conditions are required to induce them.
• The student can propose ways to make specific polymers, oligopeptides and oligosaccharides taking the intrinsic reactivity of the monomers into account.
• The student can predict regioselectivity in (heterocyclic) aromatic compounds, also when activating/deactivating substituents are present in the molecule .
• The student can predict the outcomes of cycloaddition reactions and electrocyclic ring closures based on molecule structure and reaction conditions.
• The student is able to propose which molecule is formed from given starting materials and reaction conditions based on considerations of reactivity.
• The student is able to perform retrosynthetic steps and hereby propose ways to make a molecule.

Beoordelingsmethode

Written examination (Plain paper)