Digital technologies transform the fundamental nature of organizations. In the era digitialization, organizations in many domains are challenged to improve or radically change their operations using digital technologies. To operate and survive in the modern business ecosystem, organizations require an effective adoption of digital technologies – in particular, software systems, such as Enterprise Resource Planning (ERP), Customer Relationship Management (CRM), Supply Chain Management (SCM) systems. After a detailed introduction to the topic of enterprise systems, we discuss the strategic importance of the effective use of them. We then focus our attention on the main types, basic issues related to the selection, implementation, architecture, and use of such systems. We also give a hands-on experience on a commonly-used enterprise system (SAP ERP System).