On exploring 1600-nm optical coherence tomo-graphy for imaging and analysis of biological tissue

Student thesis: Master


Optical Coherence Tomography (OCT) is a growing field of research in medical imaging, as it allows for imaging of tissue in depth. This research contributes by building a pioneering system for biomedical tissue analysis, using higher wavelengths then currently used, in order to increase penetration depth in tissue. In this paper, a dedicated Swept Source Optical Coherence Tomography (OCT) setup for medical imaging is presented and discussed. Also the possibilities for image analysis are introduced and methods that are currently used in ophthalmology are discussed as possibilities in OCT imaging of other tissue. This research first focuses on the development of a first OCT setup at 1600 nm and its involved challenges and the first experimental analysis of the images provided by the OCT system. Also, a comparison is made between the OCT images and ultrasound images and the analysis techniques typically applied in that field of medical imaging. First image segmentation results show promising region identification within the OCT images.
Date of Award28 Feb 2015
Original languageEnglish
SupervisorErwin A.J.M. Bente (Supervisor 1) & Svitlana Zinger (Supervisor 2)

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