Whole brain 31P MRSI at 7T with a dual-tuned receive array

Benjamin C. Rowland, Ian D. Driver, Mohamed Tachrount, Dennis W.J. Klomp, Debra Rivera, Ria Forner, Anh Pham, Michel Italiaander, Richard G. Wise

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Abstract

Purpose: The design and performance of a novel head coil setup for (Formula presented.) P spectroscopy at ultra-high field strengths (7T) is presented. The described system supports measurements at both the (Formula presented.) H and (Formula presented.) P resonance frequencies. Methods: The novel coil consists of 2, actively detunable, coaxial birdcage coils to give homogeneous transmit, combined with a double resonant 30 channel receive array. This allows for anatomical imaging combined with (Formula presented.) P acquisitions over the whole head, without changing coils or disturbing the subject. A phosphate buffer phantom and 3 healthy volunteers were scanned with a pulse acquire CSI sequence using both the novel array coil and a conventional transceiver birdcage. Four different methods of combining the array channels were compared at 3 different levels of SNR. Results: The novel coil setup delivers significantly increased (Formula presented.) P SNR in the peripheral regions of the brain, reaching up to factor 8, while maintaining comparable performance relative to the birdcage in the center. Conclusions: The new system offers the potential to acquire whole brain (Formula presented.) P MRSI with superior signal relative to the standard options.

Original languageEnglish
Pages (from-to)765-775
Number of pages11
JournalMagnetic Resonance in Medicine
Volume83
Issue number2
DOIs
Publication statusPublished - 1 Feb 2020

Keywords

  • 31P
  • dual-tuned
  • MRSI
  • phosphorus
  • receive array
  • spectroscopy
  • Protons
  • Magnetic Resonance Spectroscopy
  • Humans
  • Signal-To-Noise Ratio
  • Healthy Volunteers
  • Equipment Design
  • Brain/diagnostic imaging
  • Magnetic Resonance Imaging
  • Head/diagnostic imaging
  • Phosphorus/chemistry
  • Image Processing, Computer-Assisted/methods
  • Phantoms, Imaging

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