Watching block copolymer self-assembly with liquid phase transmission electron microscopy

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Abstract

Amphiphilic block copolymers in soln. can assembly into a wide range of colloidal materials, which have been widely investigated as drug delivery vehicles and catalytic nanoreactors. Due to their kinetically trapped nature, self-​assembly is often performed using the solvent switch protocol. While numerous exptl. and theor. investigations into the mechanism of self-​assembly have been conducted in an effort to gain more control over this process, there has never been a real-​time, real space investigation of the assembly process on the nanoscale. Here we present the first observation of block copolymer assembly via the solvent switch process using liq. phase transmission electron microscopy. We show the formation of polymer vesicles, cylindrical micelles and multicompartmental structures and discuss the different mechanisms of self-​assembly with supporting data from ex-​situ cryoTEM measurements and SCF (SCF) lattice computations.
LanguageEnglish
Title of host publicationAbstracts of Papers, 255th ACS National Meeting & Exposition
PublisherAmerican Chemical Society
StatePublished - 18 Mar 2018
Event

255th ACS National Meeting

- New Orleans Convention Center, New Orleans, United States
Duration: 18 Mar 201822 Mar 2018

Conference

Conference

255th ACS National Meeting

CountryUnited States
CityNew Orleans
Period18/03/1822/03/18

Fingerprint

block copolymers
self assembly
liquid phases
assembly
transmission electron microscopy
self consistent fields
switches
delivery
micelles
vehicles
drugs
polymers

Cite this

Wu, H., Ianiro, A., van Rijt, M., de Carvalho Esteves, C., Friedrich, H., Tuinier, R., ... Patterson, J. (2018). Watching block copolymer self-assembly with liquid phase transmission electron microscopy. In Abstracts of Papers, 255th ACS National Meeting & Exposition [POLY 295] American Chemical Society.
Wu, Hanglong ; Ianiro, Alessandro ; van Rijt, Mark ; de Carvalho Esteves, Catarina ; Friedrich, Heiner ; Tuinier, Remco ; Sommerdijk, Nico ; Patterson, Joseph. / Watching block copolymer self-assembly with liquid phase transmission electron microscopy. Abstracts of Papers, 255th ACS National Meeting & Exposition. American Chemical Society, 2018.
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title = "Watching block copolymer self-assembly with liquid phase transmission electron microscopy",
abstract = "Amphiphilic block copolymers in soln. can assembly into a wide range of colloidal materials, which have been widely investigated as drug delivery vehicles and catalytic nanoreactors. Due to their kinetically trapped nature, self-​assembly is often performed using the solvent switch protocol. While numerous exptl. and theor. investigations into the mechanism of self-​assembly have been conducted in an effort to gain more control over this process, there has never been a real-​time, real space investigation of the assembly process on the nanoscale. Here we present the first observation of block copolymer assembly via the solvent switch process using liq. phase transmission electron microscopy. We show the formation of polymer vesicles, cylindrical micelles and multicompartmental structures and discuss the different mechanisms of self-​assembly with supporting data from ex-​situ cryoTEM measurements and SCF (SCF) lattice computations.",
author = "Hanglong Wu and Alessandro Ianiro and {van Rijt}, Mark and {de Carvalho Esteves}, Catarina and Heiner Friedrich and Remco Tuinier and Nico Sommerdijk and Joseph Patterson",
year = "2018",
month = "3",
day = "18",
language = "English",
booktitle = "Abstracts of Papers, 255th ACS National Meeting & Exposition",
publisher = "American Chemical Society",
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Wu, H, Ianiro, A, van Rijt, M, de Carvalho Esteves, C, Friedrich, H, Tuinier, R, Sommerdijk, N & Patterson, J 2018, Watching block copolymer self-assembly with liquid phase transmission electron microscopy. in Abstracts of Papers, 255th ACS National Meeting & Exposition., POLY 295, American Chemical Society,

255th ACS National Meeting

, New Orleans, United States, 18/03/18.

Watching block copolymer self-assembly with liquid phase transmission electron microscopy. / Wu, Hanglong; Ianiro, Alessandro; van Rijt, Mark; de Carvalho Esteves, Catarina; Friedrich, Heiner; Tuinier, Remco; Sommerdijk, Nico; Patterson, Joseph.

Abstracts of Papers, 255th ACS National Meeting & Exposition. American Chemical Society, 2018. POLY 295.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

TY - GEN

T1 - Watching block copolymer self-assembly with liquid phase transmission electron microscopy

AU - Wu,Hanglong

AU - Ianiro,Alessandro

AU - van Rijt,Mark

AU - de Carvalho Esteves,Catarina

AU - Friedrich,Heiner

AU - Tuinier,Remco

AU - Sommerdijk,Nico

AU - Patterson,Joseph

PY - 2018/3/18

Y1 - 2018/3/18

N2 - Amphiphilic block copolymers in soln. can assembly into a wide range of colloidal materials, which have been widely investigated as drug delivery vehicles and catalytic nanoreactors. Due to their kinetically trapped nature, self-​assembly is often performed using the solvent switch protocol. While numerous exptl. and theor. investigations into the mechanism of self-​assembly have been conducted in an effort to gain more control over this process, there has never been a real-​time, real space investigation of the assembly process on the nanoscale. Here we present the first observation of block copolymer assembly via the solvent switch process using liq. phase transmission electron microscopy. We show the formation of polymer vesicles, cylindrical micelles and multicompartmental structures and discuss the different mechanisms of self-​assembly with supporting data from ex-​situ cryoTEM measurements and SCF (SCF) lattice computations.

AB - Amphiphilic block copolymers in soln. can assembly into a wide range of colloidal materials, which have been widely investigated as drug delivery vehicles and catalytic nanoreactors. Due to their kinetically trapped nature, self-​assembly is often performed using the solvent switch protocol. While numerous exptl. and theor. investigations into the mechanism of self-​assembly have been conducted in an effort to gain more control over this process, there has never been a real-​time, real space investigation of the assembly process on the nanoscale. Here we present the first observation of block copolymer assembly via the solvent switch process using liq. phase transmission electron microscopy. We show the formation of polymer vesicles, cylindrical micelles and multicompartmental structures and discuss the different mechanisms of self-​assembly with supporting data from ex-​situ cryoTEM measurements and SCF (SCF) lattice computations.

M3 - Conference contribution

BT - Abstracts of Papers, 255th ACS National Meeting & Exposition

PB - American Chemical Society

ER -

Wu H, Ianiro A, van Rijt M, de Carvalho Esteves C, Friedrich H, Tuinier R et al. Watching block copolymer self-assembly with liquid phase transmission electron microscopy. In Abstracts of Papers, 255th ACS National Meeting & Exposition. American Chemical Society. 2018. POLY 295.