Abstract
We studied the use of functional MRI (fMRI) with visual stimulation in nine patients with unilateral optic neuritis. Eight healthy subjects served as controls. Patients showed reduced activation upon stimulation of the affected eye, on average 33% (range 0 to 156%) of the average monocular activation in the control group. Decreased activation was also seen for the unaffected eye (61% of control values, range 3 to 133%). We conclude that fMRI with visual stimulation is feasible in patients with optic neuritis and deserves future study.
| Original language | English |
|---|---|
| Pages (from-to) | 1896-1899 |
| Number of pages | 4 |
| Journal | Neurology |
| Volume | 50 |
| Issue number | 6 |
| Publication status | Published - Jun 1998 |
| Externally published | Yes |
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Visual activation patterns in patients with optic neuritis: an fMRI pilot study. / Rombouts, S.A.R.B.; Lazeron, R.H.C.; Scheltens, P.; Uitdehaag, B.M.J.; Sprenger, M.; Valk, J.; Barkhof, F.
In: Neurology, Vol. 50, No. 6, 06.1998, p. 1896-1899.Research output: Contribution to journal › Article › Academic › peer-review
TY - JOUR
T1 - Visual activation patterns in patients with optic neuritis: an fMRI pilot study
AU - Rombouts, S.A.R.B.
AU - Lazeron, R.H.C.
AU - Scheltens, P.
AU - Uitdehaag, B.M.J.
AU - Sprenger, M.
AU - Valk, J.
AU - Barkhof, F.
PY - 1998/6
Y1 - 1998/6
N2 - We studied the use of functional MRI (fMRI) with visual stimulation in nine patients with unilateral optic neuritis. Eight healthy subjects served as controls. Patients showed reduced activation upon stimulation of the affected eye, on average 33% (range 0 to 156%) of the average monocular activation in the control group. Decreased activation was also seen for the unaffected eye (61% of control values, range 3 to 133%). We conclude that fMRI with visual stimulation is feasible in patients with optic neuritis and deserves future study.
AB - We studied the use of functional MRI (fMRI) with visual stimulation in nine patients with unilateral optic neuritis. Eight healthy subjects served as controls. Patients showed reduced activation upon stimulation of the affected eye, on average 33% (range 0 to 156%) of the average monocular activation in the control group. Decreased activation was also seen for the unaffected eye (61% of control values, range 3 to 133%). We conclude that fMRI with visual stimulation is feasible in patients with optic neuritis and deserves future study.
UR - http://www.scopus.com/inward/record.url?scp=0031746007&partnerID=8YFLogxK
M3 - Article
C2 - 9633756
AN - SCOPUS:0031746007
VL - 50
SP - 1896
EP - 1899
JO - Neurology
JF - Neurology
SN - 0028-3878
IS - 6
ER -