Visual activation patterns in patients with optic neuritis: an fMRI pilot study

S.A.R.B. Rombouts, R.H.C. Lazeron, P. Scheltens, B.M.J. Uitdehaag, M. Sprenger, J. Valk, F. Barkhof

Research output: Contribution to journalArticleAcademicpeer-review

60 Citations (Scopus)

Abstract

We studied the use of functional MRI (fMRI) with visual stimulation in nine patients with unilateral optic neuritis. Eight healthy subjects served as controls. Patients showed reduced activation upon stimulation of the affected eye, on average 33% (range 0 to 156%) of the average monocular activation in the control group. Decreased activation was also seen for the unaffected eye (61% of control values, range 3 to 133%). We conclude that fMRI with visual stimulation is feasible in patients with optic neuritis and deserves future study.

Original languageEnglish
Pages (from-to)1896-1899
Number of pages4
JournalNeurology
Volume50
Issue number6
Publication statusPublished - Jun 1998
Externally publishedYes

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