"virtual" (Computed) fractional flow reserve current challenges and limitations

P.D. Morris, F.N. Van De Vosse, P.V. Lawford, D.R. Hose, J.P. Gunn

Research output: Contribution to journalArticleAcademicpeer-review

97 Citations (Scopus)
84 Downloads (Pure)


Fractional flow reserve (FFR) is the "gold standard" for assessing the physiological significance of coronary artery disease during invasive coronary angiography. FFR-guided percutaneous coronary intervention improves patient outcomes and reduces stent insertion and cost; yet, due to several practical and operator related factors, it is used in

Original languageEnglish
Pages (from-to)1009-1017
Number of pages9
JournalJACC: Cardiovascular Interventions
Issue number8
Publication statusPublished - 1 Jul 2015


  • computational fluid dynamics
  • computational modeling
  • coronary angiography
  • fractional flow reserve
  • percutaneous coronary intervention
  • virtual fractional flow reserve


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