Validation of an aging virtual population for the study of carotid hemodynamics

Irene Suriani; R. Arthur Bouwman; Massimo Mischi; Kevin D. Lau

doi:10.1109/EMBC46164.2021.9630876

Validation of an aging virtual population for the study of carotid hemodynamics

Irene Suriani, R. Arthur Bouwman, Massimo Mischi, Kevin D. Lau

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

2 Citations (Scopus)

1 Downloads (Pure)

Abstract

The analysis of carotid ultrasound (US) flow, velocity, and diameter waveforms provides important information about cardiovascular and circulatory health. These can be used to derive clinical indices of atherosclerosis, vascular aging, and hemodynamic status. To derive clinical insight from carotid waveforms, it is essential to understand the relationship of the observed variability in morphology with the underlying hemodynamic status and cardiovascular properties. For this purpose, using a one-dimensional modeling approach, we have developed and validated a virtual population that is able to realistically simulate carotid waveforms of healthy subjects aged between 10 and 80 years old.Clinical Relevance-Our virtual population of carotid waveforms can support the interpretation of US patient data. It can be used, e.g., to investigate how waveform morphology and derived indices relate to individual arterial and cardiac properties.

Original language	English
Title of host publication	2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)
Publisher	Institute of Electrical and Electronics Engineers
Pages	4249-4252
Number of pages	4
DOIs	https://doi.org/10.1109/EMBC46164.2021.9630876
Publication status	Published - 9 Dec 2021
Event	43rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2021 - Virtual, Mexico Duration: 1 Nov 2021 → 5 Nov 2021 Conference number: 43 https://embc.embs.org/2021/

Conference

Conference	43rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2021
Abbreviated title	EMBC 2021
Country/Territory	Mexico
Period	1/11/21 → 5/11/21
Internet address	https://embc.embs.org/2021/

Funding

Research supported by eMTIC, NWO

Funders	Funder number
Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Keywords

Modeling and simulation
Virtual population
Carotid Arteries/physiology
1D pulse wave propagation modeling
Aging
Carotid Arteries/diagnostic imaging
Hemodynamics
Ultrasonography

Access to Document

10.1109/EMBC46164.2021.9630876

Cite this

Suriani, I., Bouwman, R. A., Mischi, M., & Lau, K. D. (2021). Validation of an aging virtual population for the study of carotid hemodynamics. In 2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) (pp. 4249-4252). Article 9630876 Institute of Electrical and Electronics Engineers. https://doi.org/10.1109/EMBC46164.2021.9630876

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abstract = "The analysis of carotid ultrasound (US) flow, velocity, and diameter waveforms provides important information about cardiovascular and circulatory health. These can be used to derive clinical indices of atherosclerosis, vascular aging, and hemodynamic status. To derive clinical insight from carotid waveforms, it is essential to understand the relationship of the observed variability in morphology with the underlying hemodynamic status and cardiovascular properties. For this purpose, using a one-dimensional modeling approach, we have developed and validated a virtual population that is able to realistically simulate carotid waveforms of healthy subjects aged between 10 and 80 years old.Clinical Relevance-Our virtual population of carotid waveforms can support the interpretation of US patient data. It can be used, e.g., to investigate how waveform morphology and derived indices relate to individual arterial and cardiac properties.",

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Suriani, I , Bouwman, RA , Mischi, M & Lau, KD 2021, Validation of an aging virtual population for the study of carotid hemodynamics. in 2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)., 9630876, Institute of Electrical and Electronics Engineers, pp. 4249-4252, 43rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2021
, Mexico, 1/11/21. https://doi.org/10.1109/EMBC46164.2021.9630876

Validation of an aging virtual population for the study of carotid hemodynamics. / Suriani, Irene ; Bouwman, R. Arthur ; Mischi, Massimo et al.
2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). Institute of Electrical and Electronics Engineers, 2021. p. 4249-4252 9630876.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

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Validation of an aging virtual population for the study of carotid hemodynamics

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Keywords

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