Validation of a preterm infant cardiovascular system model under baroreflex control with heart rate and blood pressure data

Ward Jennekens; Marco Dat; Peter H.M. Bovendeerd; Pieter F.F. Wijn; Peter Andriessen

doi:10.1109/IEMBS.2011.6090200

Validation of a preterm infant cardiovascular system model under baroreflex control with heart rate and blood pressure data

Ward Jennekens, Marco Dat, Peter H.M. Bovendeerd, Pieter F.F. Wijn, Peter Andriessen

Cardiovascular Biomechanics

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

7 Citations (Scopus)

1 Downloads (Pure)

Abstract

In this paper we present an autonomic cardiovascular model of a preterm infant of 28 weeks of gestation with a birth weight of 1000 g and a closed ductus arteriosus by the end of the first week, that is capable of describing the complex interactions between heart rate, blood pressure and respiration. The hemodynamic model consists of a pulsatile heart and several vascular compartments, and is regulated by a baroreflex control system. The model is relatively simple to allow for a mathematical analysis of the dynamics but sufficiently complex to provide a realistic representation of the underlying physiology. The model provides (beat-to-beat) values of R-R interval and blood pressure that resemble realistic signals of preterm infants. The model is validated with experimental data obtained in preterm infants.

Original language	English
Title of host publication	33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
Place of Publication	Piscataway
Publisher	Institute of Electrical and Electronics Engineers
Pages	896-899
Number of pages	4
ISBN (Electronic)	978-1-4577-1589-1
ISBN (Print)	978-1-4244-4121-1
DOIs	https://doi.org/10.1109/IEMBS.2011.6090200
Publication status	Published - 26 Dec 2011
Event	33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011 - Boston, MA, United States Duration: 30 Aug 2011 → 3 Sept 2011

Conference

Conference	33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
Country/Territory	United States
City	Boston, MA
Period	30/08/11 → 3/09/11

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10.1109/IEMBS.2011.6090200

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Jennekens, W., Dat, M., Bovendeerd, P. H. M., Wijn, P. F. F., & Andriessen, P. (2011). Validation of a preterm infant cardiovascular system model under baroreflex control with heart rate and blood pressure data. In 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011 (pp. 896-899). Article 6090200 Institute of Electrical and Electronics Engineers. https://doi.org/10.1109/IEMBS.2011.6090200

Jennekens, Ward ; Dat, Marco ; Bovendeerd, Peter H.M. et al. / Validation of a preterm infant cardiovascular system model under baroreflex control with heart rate and blood pressure data. 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011. Piscataway : Institute of Electrical and Electronics Engineers, 2011. pp. 896-899

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abstract = "In this paper we present an autonomic cardiovascular model of a preterm infant of 28 weeks of gestation with a birth weight of 1000 g and a closed ductus arteriosus by the end of the first week, that is capable of describing the complex interactions between heart rate, blood pressure and respiration. The hemodynamic model consists of a pulsatile heart and several vascular compartments, and is regulated by a baroreflex control system. The model is relatively simple to allow for a mathematical analysis of the dynamics but sufficiently complex to provide a realistic representation of the underlying physiology. The model provides (beat-to-beat) values of R-R interval and blood pressure that resemble realistic signals of preterm infants. The model is validated with experimental data obtained in preterm infants.",

author = "Ward Jennekens and Marco Dat and Bovendeerd, {Peter H.M.} and Wijn, {Pieter F.F.} and Peter Andriessen",

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note = "33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011 ; Conference date: 30-08-2011 Through 03-09-2011",

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Jennekens, W, Dat, M, Bovendeerd, PHM, Wijn, PFF & Andriessen, P 2011, Validation of a preterm infant cardiovascular system model under baroreflex control with heart rate and blood pressure data. in 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011., 6090200, Institute of Electrical and Electronics Engineers, Piscataway, pp. 896-899, 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011, Boston, MA, United States, 30/08/11. https://doi.org/10.1109/IEMBS.2011.6090200

Validation of a preterm infant cardiovascular system model under baroreflex control with heart rate and blood pressure data. / Jennekens, Ward; Dat, Marco; Bovendeerd, Peter H.M. et al.
33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011. Piscataway: Institute of Electrical and Electronics Engineers, 2011. p. 896-899 6090200.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

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Jennekens W, Dat M, Bovendeerd PHM, Wijn PFF, Andriessen P. Validation of a preterm infant cardiovascular system model under baroreflex control with heart rate and blood pressure data. In 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011. Piscataway: Institute of Electrical and Electronics Engineers. 2011. p. 896-899. 6090200 doi: 10.1109/IEMBS.2011.6090200

Validation of a preterm infant cardiovascular system model under baroreflex control with heart rate and blood pressure data

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