Tuning microfluidic flow by pulsed light oscillating spiropyran-basedpolymer hydrogel valves

S. Coleman; J. ter Schiphorst; A. Ben Azouz; Sterre Bakker; A.P.H.J. Schenning; D. Diamond

doi:10.1016/j.snb.2017.01.112

Tuning microfluidic flow by pulsed light oscillating spiropyran-basedpolymer hydrogel valves

S. Coleman, J. ter Schiphorst, A. Ben Azouz, Sterre Bakker, A.P.H.J. Schenning, D. Diamond

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

A method for microfluidic flow control based upon polymer hydrogel valves with rapid and reversible actuation properties is described. The platform allows for contactless optical flow control based upon pulsing light, resulting in a forced oscillating and control over the valve through photo-isomerisation of a spiropyran derivative, co-polymerised within an N-isopropylacrylamide (NIPAm) hydrogel. Application of pulsed light (450 nm) to the valves allows the valves to be held at an intermediate position for extended periods of time. Varying the extent of pulsing of the light source enables the flow rate to be regulated within a microfluidic flow rate range of 0–27 μL/min. Due to the pulsed light, a small period change in the flow rate is observed that corresponds to the pulse sequence as a corresponding oscillation in the hydrogel valves.

Original language	English
Pages (from-to)	81-86
Number of pages	6
Journal	Sensors and Actuators, B: Chemical
Volume	245
DOIs	https://doi.org/10.1016/j.snb.2017.01.112
Publication status	Published - Jun 2017

Keywords

Flow control
Microfluidics
Microvalves
Photo-responsive
Polymer
Spiropyran

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10.1016/j.snb.2017.01.112

publisher versionFinal published version, 926 KBLicence: TAVERNE

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title = "Tuning microfluidic flow by pulsed light oscillating spiropyran-basedpolymer hydrogel valves",

abstract = "A method for microfluidic flow control based upon polymer hydrogel valves with rapid and reversible actuation properties is described. The platform allows for contactless optical flow control based upon pulsing light, resulting in a forced oscillating and control over the valve through photo-isomerisation of a spiropyran derivative, co-polymerised within an N-isopropylacrylamide (NIPAm) hydrogel. Application of pulsed light (450 nm) to the valves allows the valves to be held at an intermediate position for extended periods of time. Varying the extent of pulsing of the light source enables the flow rate to be regulated within a microfluidic flow rate range of 0–27 μL/min. Due to the pulsed light, a small period change in the flow rate is observed that corresponds to the pulse sequence as a corresponding oscillation in the hydrogel valves.",

keywords = "Flow control, Microfluidics, Microvalves, Photo-responsive, Polymer, Spiropyran",

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AU - Coleman, S.

AU - ter Schiphorst, J.

AU - Ben Azouz, A.

AU - Bakker, Sterre

AU - Schenning, A.P.H.J.

AU - Diamond, D.

PY - 2017/6

Y1 - 2017/6

N2 - A method for microfluidic flow control based upon polymer hydrogel valves with rapid and reversible actuation properties is described. The platform allows for contactless optical flow control based upon pulsing light, resulting in a forced oscillating and control over the valve through photo-isomerisation of a spiropyran derivative, co-polymerised within an N-isopropylacrylamide (NIPAm) hydrogel. Application of pulsed light (450 nm) to the valves allows the valves to be held at an intermediate position for extended periods of time. Varying the extent of pulsing of the light source enables the flow rate to be regulated within a microfluidic flow rate range of 0–27 μL/min. Due to the pulsed light, a small period change in the flow rate is observed that corresponds to the pulse sequence as a corresponding oscillation in the hydrogel valves.

AB - A method for microfluidic flow control based upon polymer hydrogel valves with rapid and reversible actuation properties is described. The platform allows for contactless optical flow control based upon pulsing light, resulting in a forced oscillating and control over the valve through photo-isomerisation of a spiropyran derivative, co-polymerised within an N-isopropylacrylamide (NIPAm) hydrogel. Application of pulsed light (450 nm) to the valves allows the valves to be held at an intermediate position for extended periods of time. Varying the extent of pulsing of the light source enables the flow rate to be regulated within a microfluidic flow rate range of 0–27 μL/min. Due to the pulsed light, a small period change in the flow rate is observed that corresponds to the pulse sequence as a corresponding oscillation in the hydrogel valves.

KW - Flow control

KW - Microfluidics

KW - Microvalves

KW - Photo-responsive

KW - Polymer

KW - Spiropyran

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DO - 10.1016/j.snb.2017.01.112

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JO - Sensors and Actuators, B: Chemical

JF - Sensors and Actuators, B: Chemical

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Tuning microfluidic flow by pulsed light oscillating spiropyran-basedpolymer hydrogel valves

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Keywords

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