Tuning microfluidic flow by pulsed light oscillating spiropyran-basedpolymer hydrogel valves

S. Coleman, J. ter Schiphorst, A. Ben Azouz, Sterre Bakker, A.P.H.J. Schenning, D. Diamond

Research output: Contribution to journalArticleAcademicpeer-review

15 Citations (Scopus)

Abstract

A method for microfluidic flow control based upon polymer hydrogel valves with rapid and reversible actuation properties is described. The platform allows for contactless optical flow control based upon pulsing light, resulting in a forced oscillating and control over the valve through photo-isomerisation of a spiropyran derivative, co-polymerised within an N-isopropylacrylamide (NIPAm) hydrogel. Application of pulsed light (450 nm) to the valves allows the valves to be held at an intermediate position for extended periods of time. Varying the extent of pulsing of the light source enables the flow rate to be regulated within a microfluidic flow rate range of 0–27 μL/min. Due to the pulsed light, a small period change in the flow rate is observed that corresponds to the pulse sequence as a corresponding oscillation in the hydrogel valves.
LanguageEnglish
Pages81-86
JournalSensors and Actuators, B: Chemical
Volume245
DOIs
StatePublished - Jun 2017

Fingerprint

Hydrogel
Microfluidics
Hydrogels
Tuning
tuning
Flow rate
Flow control
flow velocity
Photoisomerization
Optical flows
Light sources
Polymers
Derivatives
actuation
isomerization
light sources
platforms
spiropyran
oscillations
polymers

Cite this

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title = "Tuning microfluidic flow by pulsed light oscillating spiropyran-basedpolymer hydrogel valves",
abstract = "A method for microfluidic flow control based upon polymer hydrogel valves with rapid and reversible actuation properties is described. The platform allows for contactless optical flow control based upon pulsing light, resulting in a forced oscillating and control over the valve through photo-isomerisation of a spiropyran derivative, co-polymerised within an N-isopropylacrylamide (NIPAm) hydrogel. Application of pulsed light (450 nm) to the valves allows the valves to be held at an intermediate position for extended periods of time. Varying the extent of pulsing of the light source enables the flow rate to be regulated within a microfluidic flow rate range of 0–27 μL/min. Due to the pulsed light, a small period change in the flow rate is observed that corresponds to the pulse sequence as a corresponding oscillation in the hydrogel valves.",
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Tuning microfluidic flow by pulsed light oscillating spiropyran-basedpolymer hydrogel valves. / Coleman, S.; ter Schiphorst, J.; Ben Azouz, A.; Bakker, Sterre; Schenning, A.P.H.J.; Diamond, D.

In: Sensors and Actuators, B: Chemical, Vol. 245, 06.2017, p. 81-86.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Tuning microfluidic flow by pulsed light oscillating spiropyran-basedpolymer hydrogel valves

AU - Coleman,S.

AU - ter Schiphorst,J.

AU - Ben Azouz,A.

AU - Bakker,Sterre

AU - Schenning,A.P.H.J.

AU - Diamond,D.

PY - 2017/6

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N2 - A method for microfluidic flow control based upon polymer hydrogel valves with rapid and reversible actuation properties is described. The platform allows for contactless optical flow control based upon pulsing light, resulting in a forced oscillating and control over the valve through photo-isomerisation of a spiropyran derivative, co-polymerised within an N-isopropylacrylamide (NIPAm) hydrogel. Application of pulsed light (450 nm) to the valves allows the valves to be held at an intermediate position for extended periods of time. Varying the extent of pulsing of the light source enables the flow rate to be regulated within a microfluidic flow rate range of 0–27 μL/min. Due to the pulsed light, a small period change in the flow rate is observed that corresponds to the pulse sequence as a corresponding oscillation in the hydrogel valves.

AB - A method for microfluidic flow control based upon polymer hydrogel valves with rapid and reversible actuation properties is described. The platform allows for contactless optical flow control based upon pulsing light, resulting in a forced oscillating and control over the valve through photo-isomerisation of a spiropyran derivative, co-polymerised within an N-isopropylacrylamide (NIPAm) hydrogel. Application of pulsed light (450 nm) to the valves allows the valves to be held at an intermediate position for extended periods of time. Varying the extent of pulsing of the light source enables the flow rate to be regulated within a microfluidic flow rate range of 0–27 μL/min. Due to the pulsed light, a small period change in the flow rate is observed that corresponds to the pulse sequence as a corresponding oscillation in the hydrogel valves.

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DO - 10.1016/j.snb.2017.01.112

M3 - Article

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EP - 86

JO - Sensors and Actuators, B: Chemical

T2 - Sensors and Actuators, B: Chemical

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SN - 0925-4005

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