Treatment of typhoid fever using ofloxacin. Clinical experience and determination of antibiotic diffusion into the mesenteric lymph nodes

J.P. Stahl, P.A. Leclercq, J. Croize, M.A. Lefebvre, J.P. Bru, J.B. Fourtillan, P. Le Noc, M. Micoud

Research output: Contribution to journalArticleAcademicpeer-review

9 Citations (Scopus)

Abstract

Nine patients with typhoid fever were given ofloxacin in a daily dosage of 400 mg for ten days. All patients recovered with no relapses. No case of Salmonella typhi carriage was recorded. Diffusion of ofloxacin into mesenteric lymph nodes was studied in four patients. Mean concentration was 1.46 micrograms/g after four 200 mg doses. According to our results, ofloxacin could be considered as one of the alternatives for treating typhoid fever.
Original languageEnglish
Pages (from-to)505-507
JournalPathologie Biologie
Volume34
Issue number5
Publication statusPublished - 1986

Fingerprint

Dive into the research topics of 'Treatment of typhoid fever using ofloxacin. Clinical experience and determination of antibiotic diffusion into the mesenteric lymph nodes'. Together they form a unique fingerprint.

Cite this