TY - JOUR
T1 - Treatment of Streptococcus mutans biofilms with a nonthermal atmospheric plasma
AU - Sladek, R.E.J.
AU - Filoche, S.K.
AU - Sissons, C.H.
AU - Stoffels - Adamowicz, E.
PY - 2007
Y1 - 2007
N2 - Aims: A nonthermal atm. plasma, designed for biomedical applications, was tested for its antimicrobial activity against biofilm cultures of a key cariogenic bacterium Streptococcus mutans. Methods and Results: The Strep. mutans biofilms were grown with and without 0.15% sucrose. A chlorhexidine digluconate rinse (0.2%) was used as a pos. antimicrobial ref. The presence of sucrose and the frequency of plasma application during growth were shown to have a significant effect on the response to treatment and antibacterial activity. Conclusions: A single plasma treatment for 1 min on biofilms cultured without sucrose caused no re-growth within the observation period. However, with either single or repeated plasma treatments of 1 min, on biofilms cultured with 0.15% sucrose, growth was only reduced. Significance and Impact of the Study: In summary, there may be a role for nonthermal plasma therapies in dental procedures. Sucrose and assocd. growth conditions may be a factor in the survival of oral biofilms after treatment.
AB - Aims: A nonthermal atm. plasma, designed for biomedical applications, was tested for its antimicrobial activity against biofilm cultures of a key cariogenic bacterium Streptococcus mutans. Methods and Results: The Strep. mutans biofilms were grown with and without 0.15% sucrose. A chlorhexidine digluconate rinse (0.2%) was used as a pos. antimicrobial ref. The presence of sucrose and the frequency of plasma application during growth were shown to have a significant effect on the response to treatment and antibacterial activity. Conclusions: A single plasma treatment for 1 min on biofilms cultured without sucrose caused no re-growth within the observation period. However, with either single or repeated plasma treatments of 1 min, on biofilms cultured with 0.15% sucrose, growth was only reduced. Significance and Impact of the Study: In summary, there may be a role for nonthermal plasma therapies in dental procedures. Sucrose and assocd. growth conditions may be a factor in the survival of oral biofilms after treatment.
U2 - 10.1111/j.1472-765X.2007.02194.x
DO - 10.1111/j.1472-765X.2007.02194.x
M3 - Article
VL - 45
SP - 318
EP - 323
JO - Letters in Applied Microbiology
JF - Letters in Applied Microbiology
SN - 0266-8254
IS - 3
ER -