Transcatheter-delivered expandable bioresorbable polymeric graft with stenting capacity induces vascular regeneration

Renee Duijvelshoff, Maria S. Cabrera, Bart Sanders, Sylvia Dekker, Anthal I.P.M. Smits, Frank P.T. Baaijens, Carlijn V.C. Bouten (Corresponding author)

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

As the next step in the translation of vascular tissue engineering, this study uniquely combines transcatheter delivery and in situ tissue regeneration using a novel bioresorbable electrospun polymer graft that can be implanted minimally invasively. Once delivered inside a small-diameter vessel, the electrospun microstructure supports the vessel wall, facilitates cellular infiltration, and guides organized tissue formation.
Original languageEnglish
Pages (from-to)1095-1110
Number of pages16
JournalJACC: Basic to Translational Science
Volume5
Issue number11
DOIs
Publication statusPublished - Nov 2020

Keywords

  • elastin
  • regeneration
  • tissue engineering
  • transcatheter delivery
  • vascular graft

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