Transcatheter-delivered expandable bioresorbable polymeric graft with stenting capacity induces vascular regeneration

Renee Duijvelshoff; Maria S. Cabrera; Bart Sanders; Sylvia Dekker; Anthal I.P.M. Smits; Frank P.T. Baaijens; Carlijn V.C. Bouten

doi:10.1016/j.jacbts.2020.09.005

Transcatheter-delivered expandable bioresorbable polymeric graft with stenting capacity induces vascular regeneration

Renee Duijvelshoff, Maria S. Cabrera, Bart Sanders, Sylvia Dekker, Anthal I.P.M. Smits, Frank P.T. Baaijens, Carlijn V.C. Bouten (Corresponding author)

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

As the next step in the translation of vascular tissue engineering, this study uniquely combines transcatheter delivery and in situ tissue regeneration using a novel bioresorbable electrospun polymer graft that can be implanted minimally invasively. Once delivered inside a small-diameter vessel, the electrospun microstructure supports the vessel wall, facilitates cellular infiltration, and guides organized tissue formation.

Original language	English
Pages (from-to)	1095-1110
Number of pages	16
Journal	JACC: Basic to Translational Science
Volume	5
Issue number	11
DOIs	https://doi.org/10.1016/j.jacbts.2020.09.005
Publication status	Published - Nov 2020

Keywords

elastin
regeneration
tissue engineering
transcatheter delivery
vascular graft

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title = "Transcatheter-delivered expandable bioresorbable polymeric graft with stenting capacity induces vascular regeneration",

abstract = "As the next step in the translation of vascular tissue engineering, this study uniquely combines transcatheter delivery and in situ tissue regeneration using a novel bioresorbable electrospun polymer graft that can be implanted minimally invasively. Once delivered inside a small-diameter vessel, the electrospun microstructure supports the vessel wall, facilitates cellular infiltration, and guides organized tissue formation.",

keywords = "elastin, regeneration, tissue engineering, transcatheter delivery, vascular graft",

author = "Renee Duijvelshoff and Cabrera, {Maria S.} and Bart Sanders and Sylvia Dekker and Smits, {Anthal I.P.M.} and Baaijens, {Frank P.T.} and Bouten, {Carlijn V.C.}",

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month = nov,

doi = "10.1016/j.jacbts.2020.09.005",

language = "English",

volume = "5",

pages = "1095--1110",

journal = "JACC: Basic to Translational Science",

issn = "2452-302X",

publisher = "Elsevier",

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}

Transcatheter-delivered expandable bioresorbable polymeric graft with stenting capacity induces vascular regeneration. / Duijvelshoff, Renee; Cabrera, Maria S.; Sanders, Bart; Dekker, Sylvia; Smits, Anthal I.P.M.; Baaijens, Frank P.T.; Bouten, Carlijn V.C. (Corresponding author).

In: JACC: Basic to Translational Science, Vol. 5, No. 11, 11.2020, p. 1095-1110.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Transcatheter-delivered expandable bioresorbable polymeric graft with stenting capacity induces vascular regeneration

AU - Duijvelshoff, Renee

AU - Cabrera, Maria S.

AU - Sanders, Bart

AU - Dekker, Sylvia

AU - Smits, Anthal I.P.M.

AU - Baaijens, Frank P.T.

AU - Bouten, Carlijn V.C.

PY - 2020/11

Y1 - 2020/11

N2 - As the next step in the translation of vascular tissue engineering, this study uniquely combines transcatheter delivery and in situ tissue regeneration using a novel bioresorbable electrospun polymer graft that can be implanted minimally invasively. Once delivered inside a small-diameter vessel, the electrospun microstructure supports the vessel wall, facilitates cellular infiltration, and guides organized tissue formation.

AB - As the next step in the translation of vascular tissue engineering, this study uniquely combines transcatheter delivery and in situ tissue regeneration using a novel bioresorbable electrospun polymer graft that can be implanted minimally invasively. Once delivered inside a small-diameter vessel, the electrospun microstructure supports the vessel wall, facilitates cellular infiltration, and guides organized tissue formation.

KW - elastin

KW - regeneration

KW - tissue engineering

KW - transcatheter delivery

KW - vascular graft

U2 - 10.1016/j.jacbts.2020.09.005

DO - 10.1016/j.jacbts.2020.09.005

M3 - Article

C2 - 33294741

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JO - JACC: Basic to Translational Science

JF - JACC: Basic to Translational Science

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Transcatheter-delivered expandable bioresorbable polymeric graft with stenting capacity induces vascular regeneration

Abstract

Keywords

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One step closer to regenerative heart valves and stents

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