Trabecular and subchondral bone development of the talus and distal tibia from foal to adult in the warmblood horse

B.M.C. Gorissen, C.F. Wolschrijn, B. van Rietbergen, L. Rieppo, S. Saarakkala, P.R. van Weeren

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Abstract

Horses are precocial animals and able to stand and walk within hours after birth. To cope with associated loading, intrauterine bone development has shown to be anticipative. This study provides further insight into the post-natal development of structurally important features of trabecular and subchondral bone of the talus and sagittal ridge of the tibia of warm-blooded horses. In all areas studied, the average bone volume fraction showed a gradual increase over time, which was the result of a significant increase in trabecular thickness, without significant changes in the degree of anisotropy. Similar to the mineralised part of the bone, collagen content, measured as average retardation using polarised light microscopy, increased significantly, but the degree of anisotropy of the collagen type I network did not. At birth, the subchondral bone layer had a more trabecular aspect, gradually changing to an even surface with only a few vascular canals at an age of 2 months. Presented results indicate the necessity for a stronger structure, but not for a different structural design after birth, providing further evidence for anticipatory bone development in the horse. More knowledge about the strategies used to cope with mechanical loading after birth might be helpful in understanding the developmental bone and joint diseases.

Original languageEnglish
Pages (from-to)206-215
JournalAnatomia, histologia, embryologia
Volume47
Issue number3
Early online date27 Feb 2018
DOIs
Publication statusPublished - 1 Jun 2018

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Talus
skeletal development
Bone Development
tibia
Tibia
foals
Horses
bones
Parturition
horses
Anisotropy
Bone and Bones
collagen
Developmental Bone Disease
Polarization Microscopy
bone diseases
joint diseases
polarized light
Joint Diseases
postnatal development

Keywords

  • Journal Article

Cite this

Gorissen, B.M.C. ; Wolschrijn, C.F. ; van Rietbergen, B. ; Rieppo, L. ; Saarakkala, S. ; van Weeren, P.R. / Trabecular and subchondral bone development of the talus and distal tibia from foal to adult in the warmblood horse. In: Anatomia, histologia, embryologia. 2018 ; Vol. 47, No. 3. pp. 206-215.
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Trabecular and subchondral bone development of the talus and distal tibia from foal to adult in the warmblood horse. / Gorissen, B.M.C.; Wolschrijn, C.F.; van Rietbergen, B.; Rieppo, L.; Saarakkala, S.; van Weeren, P.R.

In: Anatomia, histologia, embryologia, Vol. 47, No. 3, 01.06.2018, p. 206-215.

Research output: Contribution to journalArticleAcademicpeer-review

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AU - Gorissen, B.M.C.

AU - Wolschrijn, C.F.

AU - van Rietbergen, B.

AU - Rieppo, L.

AU - Saarakkala, S.

AU - van Weeren, P.R.

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N2 - Horses are precocial animals and able to stand and walk within hours after birth. To cope with associated loading, intrauterine bone development has shown to be anticipative. This study provides further insight into the post-natal development of structurally important features of trabecular and subchondral bone of the talus and sagittal ridge of the tibia of warm-blooded horses. In all areas studied, the average bone volume fraction showed a gradual increase over time, which was the result of a significant increase in trabecular thickness, without significant changes in the degree of anisotropy. Similar to the mineralised part of the bone, collagen content, measured as average retardation using polarised light microscopy, increased significantly, but the degree of anisotropy of the collagen type I network did not. At birth, the subchondral bone layer had a more trabecular aspect, gradually changing to an even surface with only a few vascular canals at an age of 2 months. Presented results indicate the necessity for a stronger structure, but not for a different structural design after birth, providing further evidence for anticipatory bone development in the horse. More knowledge about the strategies used to cope with mechanical loading after birth might be helpful in understanding the developmental bone and joint diseases.

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