@article{b8cbe7c1248f44eea166a30f2f925ccd,
title = "Towards ultrahigh resolution OCT based endoscopical pituitary gland and adenoma screening: a performance parameter evaluation",
abstract = "Ultrahigh resolution optical coherence tomography (UHR-OCT) for differentiating pituitary gland versus adenoma tissue has been investigated for the first time, indicating more than 80% accuracy. For biomarker identification, OCT images of paraffin embedded tissue are correlated to histopathological slices. The identified biomarkers are verified on fresh biopsies. Additionally, an approach, based on resolution modified UHR-OCT ex vivo data, investigating optical performance parameters for the realization in an in vivo endoscope is presented and evaluated. The identified morphological features–cell groups with reticulin framework–detectable with UHR-OCT showcase a promising differentiation ability, encouraging endoscopic OCT probe development for in vivo application.",
keywords = "Biomarkers, Brain, Coherent light, Endoscopy, Tumors, Optical tomography",
author = "Fabian Placzek and Alexander Micko and Ryan Sentosa and Roger Fonoll{\`a} and Michael Winklehner and Arthur Hosmann and Marco Andreana and Romana H{\"o}ftberger and Wolfgang Drexler and Leitgeb, {Rainer A.} and Stefan Wolfsberger and Angelika Unterhuber",
year = "2020",
month = dec,
day = "1",
doi = "10.1364/BOE.409987",
language = "English",
volume = "11",
pages = "7003--7018",
journal = "Biomedical Optics Express",
issn = "2156-7085",
publisher = "Optica Publishing Group",
number = "12",
}