Abstract
The main indicator for endarterectomy is the grade of stenosis, which results in severe overtreatment. Photoacoustic imaging (PAI) can provide patient-specific assessment of plaque morphology, and thereby vulnerability. A pilot study of PAI on carotid plaques in patients (n=16) was performed intraoperatively with a hand-held PAI system. By compensating for motion, the photoacoustic (PA) signal-to-noise ratio (SNR) could be increased by 5 dB in vivo. PA signals from hemorrhagic plaques had different characteristics compared to the signals from the carotid blood pool. This study is a key step towards a non-invasive application of PAI to detect vulnerable plaques.
Original language | English |
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Pages (from-to) | 4207-4218 |
Number of pages | 12 |
Journal | Biomedical Optics Express |
Volume | 12 |
Issue number | 7 |
DOIs | |
Publication status | Published - 1 Jul 2021 |
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Cardiovascular Medicine
van de Laar, L. (Content manager) & Jansen, J. (Content manager)
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