### Abstract

Original language | English |
---|---|

Pages (from-to) | 317-324 |

Journal | Biophysical Chemistry |

Volume | 31 |

Issue number | 3 |

DOIs | |

Publication status | Published - 1988 |

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*Biophysical Chemistry*,

*31*(3), 317-324. https://doi.org/10.1016/0301-4622(88)80038-3

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*Biophysical Chemistry*, vol. 31, no. 3, pp. 317-324. https://doi.org/10.1016/0301-4622(88)80038-3

**Time-dependent ligand current into a saturating cell performing chemoreception.** / Geurts, B.J.; Wiegel, F.W.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Time-dependent ligand current into a saturating cell performing chemoreception

AU - Geurts, B.J.

AU - Wiegel, F.W.

PY - 1988

Y1 - 1988

N2 - We determine the ligand current into a single spherical cell whose receptors become permanently blocked after binding ligands. Initially the cell is placed in a medium which contains ligands at uniform concentration. The analytical solution for the ligand distribution is obtained in terms of an integral over the solution at the cell surface. For the solution at the cell surface a nonlinear integral equation is derived which is solved numerically. We determine the time-dependent ligand current into the cell and the average number of free receptors in the cell surface as a function of time

AB - We determine the ligand current into a single spherical cell whose receptors become permanently blocked after binding ligands. Initially the cell is placed in a medium which contains ligands at uniform concentration. The analytical solution for the ligand distribution is obtained in terms of an integral over the solution at the cell surface. For the solution at the cell surface a nonlinear integral equation is derived which is solved numerically. We determine the time-dependent ligand current into the cell and the average number of free receptors in the cell surface as a function of time

U2 - 10.1016/0301-4622(88)80038-3

DO - 10.1016/0301-4622(88)80038-3

M3 - Article

VL - 31

SP - 317

EP - 324

JO - Biophysical Chemistry

JF - Biophysical Chemistry

SN - 0301-4622

IS - 3

ER -