The initial stages of template-controlled CaCO3 formation revealed by Cryo-TEM

E.M. Pouget; P.H.H. Bomans; J.A.C.M. Goos; P.M. Frederik; G. With, de; N.A.J.M. Sommerdijk

doi:10.1126/science.1169434

The initial stages of template-controlled CaCO3 formation revealed by Cryo-TEM

E.M. Pouget, P.H.H. Bomans, J.A.C.M. Goos, P.M. Frederik, G. With, de, N.A.J.M. Sommerdijk

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Abstract

Biogenic calcium carbonate forms the inorganic component of seashells, otoliths, and many marineskeletons, and its formation is directed by an ordered template of macromolecules. Classicalnucleation theory considers crystal formation to occur from a critical nucleus formed by theassembly of ions from solution. Using cryotransmission electron microscopy, we found thattemplate-directed calcium carbonate formation starts with the formation of prenucleation clusters.Their aggregation leads to the nucleation of amorphous nanoparticles in solution. Thesenanoparticles assemble at the template and, after reaching a critical size, develop dynamiccrystalline domains, one of which is selectively stabilized by the template. Our findings haveimplications for template-directed mineral formation in biological as well as in synthetic systems.

Original language	English
Pages (from-to)	1455-1458
Journal	Science
Volume	323
Issue number	5920
DOIs	https://doi.org/10.1126/science.1169434
Publication status	Published - 2009

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Center for Multiscale Electron Microscopy (CMEM)
Heiner Friedrich (Manager), Rick Joosten (Education/research officer), Pauline Schmit (Education/research officer), Ingeborg Schreur - Piet (Other) & Anne Spoelstra (Education/research officer)
Physical Chemistry
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title = "The initial stages of template-controlled CaCO3 formation revealed by Cryo-TEM",

abstract = "Biogenic calcium carbonate forms the inorganic component of seashells, otoliths, and many marineskeletons, and its formation is directed by an ordered template of macromolecules. Classicalnucleation theory considers crystal formation to occur from a critical nucleus formed by theassembly of ions from solution. Using cryotransmission electron microscopy, we found thattemplate-directed calcium carbonate formation starts with the formation of prenucleation clusters.Their aggregation leads to the nucleation of amorphous nanoparticles in solution. Thesenanoparticles assemble at the template and, after reaching a critical size, develop dynamiccrystalline domains, one of which is selectively stabilized by the template. Our findings haveimplications for template-directed mineral formation in biological as well as in synthetic systems.",

author = "E.M. Pouget and P.H.H. Bomans and J.A.C.M. Goos and P.M. Frederik and {With, de}, G. and N.A.J.M. Sommerdijk",

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doi = "10.1126/science.1169434",

language = "English",

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T1 - The initial stages of template-controlled CaCO3 formation revealed by Cryo-TEM

AU - Pouget, E.M.

AU - Bomans, P.H.H.

AU - Goos, J.A.C.M.

AU - Frederik, P.M.

AU - With, de, G.

AU - Sommerdijk, N.A.J.M.

PY - 2009

Y1 - 2009

N2 - Biogenic calcium carbonate forms the inorganic component of seashells, otoliths, and many marineskeletons, and its formation is directed by an ordered template of macromolecules. Classicalnucleation theory considers crystal formation to occur from a critical nucleus formed by theassembly of ions from solution. Using cryotransmission electron microscopy, we found thattemplate-directed calcium carbonate formation starts with the formation of prenucleation clusters.Their aggregation leads to the nucleation of amorphous nanoparticles in solution. Thesenanoparticles assemble at the template and, after reaching a critical size, develop dynamiccrystalline domains, one of which is selectively stabilized by the template. Our findings haveimplications for template-directed mineral formation in biological as well as in synthetic systems.

AB - Biogenic calcium carbonate forms the inorganic component of seashells, otoliths, and many marineskeletons, and its formation is directed by an ordered template of macromolecules. Classicalnucleation theory considers crystal formation to occur from a critical nucleus formed by theassembly of ions from solution. Using cryotransmission electron microscopy, we found thattemplate-directed calcium carbonate formation starts with the formation of prenucleation clusters.Their aggregation leads to the nucleation of amorphous nanoparticles in solution. Thesenanoparticles assemble at the template and, after reaching a critical size, develop dynamiccrystalline domains, one of which is selectively stabilized by the template. Our findings haveimplications for template-directed mineral formation in biological as well as in synthetic systems.

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DO - 10.1126/science.1169434

M3 - Article

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VL - 323

SP - 1455

EP - 1458

JO - Science

JF - Science

SN - 0036-8075

IS - 5920

ER -

The initial stages of template-controlled CaCO3 formation revealed by Cryo-TEM

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