The impact of plant-pathogen studies on medicinal drug discovery

C. Ottmann, R.A.L. Hoorn, van der, M. Kaiser

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)
2 Downloads (Pure)


The pharmaceutical industry is reliant on a constant supply of new chemical entities and molecular targets for disease intervention. In this tutorial review, we want to illustrate that basic research studies on the biological function of natural products involved in plant–pathogen interactions can serve as an inspiring source for the identification of new bioactive entities as well as of strategies on how to achieve small molecule manipulation of biological systems. An application of findings from plant–pathogen interaction studies might therefore display a significant impact on drug discovery.
Original languageEnglish
Pages (from-to)3168-3178
Number of pages11
JournalChemical Society Reviews
Issue number8
Publication statusPublished - 2012


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