The first small-molecule inhibitor of 14-3-3s : modulating the master regulator

M. Kaiser; C. Ottmann

doi:10.1002/cbic.201000483

The first small-molecule inhibitor of 14-3-3s : modulating the master regulator

M. Kaiser, C. Ottmann

Chemical Biology

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

Adapting the adapter: The identification, synthesis and cellular activity of the first 14-3-3 protein–protein interaction inhibitor have recently been reported. This success opens up new possibilities for small-molecule modulation of the biology of these important adapter proteins with the potential for new therapeutic approaches.

Original language	English
Pages (from-to)	2085-2087
Number of pages	3
Journal	ChemBioChem
Volume	11
Issue number	15
DOIs	https://doi.org/10.1002/cbic.201000483
Publication status	Published - 2010

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abstract = "Adapting the adapter: The identification, synthesis and cellular activity of the first 14-3-3 protein–protein interaction inhibitor have recently been reported. This success opens up new possibilities for small-molecule modulation of the biology of these important adapter proteins with the potential for new therapeutic approaches.",

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The first small-molecule inhibitor of 14-3-3s : modulating the master regulator

Abstract

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