The convenient synthesis of hydrogen-bonded ureidopyrimidinones

H.M. Keizer; R.P. Sijbesma; E.W. Meijer

doi:10.1002/ejoc.200300752

The convenient synthesis of hydrogen-bonded ureidopyrimidinones

H.M. Keizer, R.P. Sijbesma, E.W. Meijer

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Abstract

Blocked isocytosine isocyanates are conveniently obtained by the reaction of 1,1'-carbonyldiimidazole (CDI) with isocytosines. The resulting precursors for quadruple hydrogen-bonded structures can be isolated and stored for further use. Reaction with either aliph. or arom. amines gives the corresponding mono-, bi-, or trifunctional ureidopyrimidinone derivs. in good to excellent isolated yields.

Original language	English
Pages (from-to)	2553-2555
Number of pages	3
Journal	European Journal of Organic Chemistry
Volume	2004
Issue number	12
DOIs	https://doi.org/10.1002/ejoc.200300752
Publication status	Published - 2004

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title = "The convenient synthesis of hydrogen-bonded ureidopyrimidinones",

abstract = "Blocked isocytosine isocyanates are conveniently obtained by the reaction of 1,1'-carbonyldiimidazole (CDI) with isocytosines. The resulting precursors for quadruple hydrogen-bonded structures can be isolated and stored for further use. Reaction with either aliph. or arom. amines gives the corresponding mono-, bi-, or trifunctional ureidopyrimidinone derivs. in good to excellent isolated yields.",

author = "H.M. Keizer and R.P. Sijbesma and E.W. Meijer",

year = "2004",

doi = "10.1002/ejoc.200300752",

language = "English",

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T1 - The convenient synthesis of hydrogen-bonded ureidopyrimidinones

AU - Keizer, H.M.

AU - Sijbesma, R.P.

AU - Meijer, E.W.

PY - 2004

Y1 - 2004

N2 - Blocked isocytosine isocyanates are conveniently obtained by the reaction of 1,1'-carbonyldiimidazole (CDI) with isocytosines. The resulting precursors for quadruple hydrogen-bonded structures can be isolated and stored for further use. Reaction with either aliph. or arom. amines gives the corresponding mono-, bi-, or trifunctional ureidopyrimidinone derivs. in good to excellent isolated yields.

AB - Blocked isocytosine isocyanates are conveniently obtained by the reaction of 1,1'-carbonyldiimidazole (CDI) with isocytosines. The resulting precursors for quadruple hydrogen-bonded structures can be isolated and stored for further use. Reaction with either aliph. or arom. amines gives the corresponding mono-, bi-, or trifunctional ureidopyrimidinone derivs. in good to excellent isolated yields.

U2 - 10.1002/ejoc.200300752

DO - 10.1002/ejoc.200300752

M3 - Article

SN - 1434-193X

VL - 2004

SP - 2553

EP - 2555

JO - European Journal of Organic Chemistry

JF - European Journal of Organic Chemistry

IS - 12

ER -

The convenient synthesis of hydrogen-bonded ureidopyrimidinones

Abstract

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