TY - JOUR
T1 - The 2-(acetoxymethyl)benzoyl (AMB) group as a new base-protecting group, designed for the protection of (phosphate) modified oligonucleotides.
AU - Kuijpers, W.H.A.
AU - Huskens, J.
AU - Boeckel, van, C.A.A.
PY - 1990
Y1 - 1990
N2 - The 2-(acetoxymethyl)benzoyl (AMB) group is a new base-protecting group that facilitates the synthesis of labile, modified nucleotides, since it can be rapidly cleaved under mild basic conditions.
The 2-(acetoxymethyl)benzoyl (AMB) group is a new base-protecting group that facilitates the synthesis of labile, modified nucleotides, since it can be rapidly cleaved under mild basic conditions: 0.05 M K2CO3/MeOH (r.t.) 30–60 min.; 32% aq. ammonia (r.t.) 1–2 hr.
AB - The 2-(acetoxymethyl)benzoyl (AMB) group is a new base-protecting group that facilitates the synthesis of labile, modified nucleotides, since it can be rapidly cleaved under mild basic conditions.
The 2-(acetoxymethyl)benzoyl (AMB) group is a new base-protecting group that facilitates the synthesis of labile, modified nucleotides, since it can be rapidly cleaved under mild basic conditions: 0.05 M K2CO3/MeOH (r.t.) 30–60 min.; 32% aq. ammonia (r.t.) 1–2 hr.
U2 - 10.1016/S0040-4039(00)97159-4
DO - 10.1016/S0040-4039(00)97159-4
M3 - Article
SN - 0040-4039
VL - 31
SP - 6729
EP - 6732
JO - Tetrahedron Letters
JF - Tetrahedron Letters
IS - 46
ER -