Abstract
We present a study on the application of tethered particle motion (TPM) for biosensing. Specifically, we investigate the dynamics of surface bound particles using TPM. In a model system, we demonstrate that particle binding to a sensor surface can be controlled via single tethers and via multiple tethers, and that the binding types can be quantified with TPM in an optical biosensing system.
| Original language | English |
|---|---|
| Title of host publication | 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 2303-2305 |
| Number of pages | 3 |
| ISBN (Electronic) | 9780979806476 |
| Publication status | Published - 1 Jan 2014 |
| Event | 18th Intermational Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2014) - San Antonio, United States Duration: 26 Oct 2014 → 30 Oct 2014 Conference number: 18 http://www.microtasconferences.org/microtas2014/ |
Conference
| Conference | 18th Intermational Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2014) |
|---|---|
| Abbreviated title | MicroTAS 2014 |
| Country | United States |
| City | San Antonio |
| Period | 26/10/14 → 30/10/14 |
| Internet address |
Keywords
- Biosensing
- Bond discrimination
- Bond dynamics
- Particles
- Tethered particle motion
Fingerprint Dive into the research topics of 'Tethered particle motion (TPM) characterizes binding types for lab-on-a-chip biosensing'. Together they form a unique fingerprint.
Cite this
Visser, E. W. A., IJzendoorn, van, L. J., & Prins, M. W. J. (2014). Tethered particle motion (TPM) characterizes binding types for lab-on-a-chip biosensing. In 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 (pp. 2303-2305). Chemical and Biological Microsystems Society.