Abstract
We present a study on the application of tethered particle motion (TPM) for biosensing. Specifically, we investigate the dynamics of surface bound particles using TPM. In a model system, we demonstrate that particle binding to a sensor surface can be controlled via single tethers and via multiple tethers, and that the binding types can be quantified with TPM in an optical biosensing system.
Original language | English |
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Title of host publication | 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 |
Publisher | Royal Society of Chemistry |
Pages | 2303-2305 |
Number of pages | 3 |
ISBN (Electronic) | 9780979806476 |
Publication status | Published - 1 Jan 2014 |
Event | 18th Intermational Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States Duration: 26 Oct 2014 → 30 Oct 2014 Conference number: 18 http://www.microtasconferences.org/microtas2014/ |
Conference
Conference | 18th Intermational Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 |
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Abbreviated title | MicroTAS 2014 |
Country/Territory | United States |
City | San Antonio |
Period | 26/10/14 → 30/10/14 |
Internet address |
Keywords
- Biosensing
- Bond discrimination
- Bond dynamics
- Particles
- Tethered particle motion