Abstract
Surprisingly stable N-t-BOC-2-bromo-4-hexyl-pyrrole is prepared from N-t-BOC-2-trimethylstannyl-4-hexyl-pyrrole using N-bromosuccinimide as reagent. The bromo-stannyl exchange reaction is performed quantitatively in THF at -70[ddot]C under inert atmosphere. Similarly, N-t-BOC-2-bromopyrrole and N-benzenesulfonyl-2-bromopyrrole have been synthesized from N-t-BOC-2-trimethylstannylpyrrole and N-benzenesulfonyl-2-trimethylstannylpyrrole, respectively.
Original language | English |
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Pages (from-to) | 1589-1600 |
Number of pages | 12 |
Journal | Synthetic Communications |
Volume | 25 |
Issue number | 10 |
DOIs | |
Publication status | Published - 1995 |