Synthesis and characterization of polyisocyanides derived from alanine and glycine dipeptides

J.J.L.M. Cornelissen, W.S. Graswinckel, P.J.H.M. Adams, G.H. Nachtegaal, A.P.M. Kentgens, N.A.J.M. Sommerdijk, R.J.M. Nolte

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Abstract

The synthesis and characterization of polymers derived from isocyanopeptides are described. Optically pure dipeptides based on alanine and glycine were equipped with an isocyano function and subsequently polymerized with a Ni(II) catalyst. Infrared and NMR spectroscopy indicated that the side chains of the polymers were connected by well-defined arrays of intramolecular hydrogen bonds. The weight-average molecular weights of the polymers were determined by atomic force microscopy to be 200-400 kg/mol (polydispersity index = 1.4-1.7).
Original languageEnglish
Pages (from-to)4255-4264
JournalJournal of Polymer Science, Part A: Polymer Chemistry
Volume39
Issue number24
DOIs
Publication statusPublished - 2001

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