Synthesis and characterization of polyethyl cyanoacrylate nanoparticles loaded with capreomycin sulfate

L. Zhaparova; Y.M. Tazhbayev; M.Zh. Burkeev; A.T. Kazhmuratova; T.S. Zhumagaliyeva; S.I. Ali; A.M. Herk, van

doi:10.1007/s11094-012-0724-1

Synthesis and characterization of polyethyl cyanoacrylate nanoparticles loaded with capreomycin sulfate

L. Zhaparova, Y.M. Tazhbayev, M.Zh. Burkeev, A.T. Kazhmuratova, T.S. Zhumagaliyeva, S.I. Ali, A.M. Herk, van

Research output: Contribution to journal › Article › Academic › peer-review

4 Citations (Scopus)

3 Downloads (Pure)

Abstract

Some aspects of the synthesis and characterization of polyethyl cyanoacrylate nanoparticles loaded with the antituberculosis drug capreomycin sulfate are considered in this work. Polyethyl cyanoacrylate nanoparticles containing capreomycin sulfate have been synthesized using anionic polymerization in emulsion. Optimum conditions of immobilization of the drug into the polymeric matrix have been found. It was determined that to increase the loading efficiency of the drug, it has to be added into the reaction medium after polymerization has started.

Original language	English
Pages (from-to)	6-9
Number of pages	4
Journal	Pharmaceutical Chemistry Journal
Volume	46
Issue number	1
DOIs	https://doi.org/10.1007/s11094-012-0724-1
Publication status	Published - 2012

Access to Document

10.1007/s11094-012-0724-1

Cite this

@article{9aa28b65c3ab480ab4eaebd0db16ee6f,

title = "Synthesis and characterization of polyethyl cyanoacrylate nanoparticles loaded with capreomycin sulfate",

abstract = "Some aspects of the synthesis and characterization of polyethyl cyanoacrylate nanoparticles loaded with the antituberculosis drug capreomycin sulfate are considered in this work. Polyethyl cyanoacrylate nanoparticles containing capreomycin sulfate have been synthesized using anionic polymerization in emulsion. Optimum conditions of immobilization of the drug into the polymeric matrix have been found. It was determined that to increase the loading efficiency of the drug, it has to be added into the reaction medium after polymerization has started.",

author = "L. Zhaparova and Y.M. Tazhbayev and M.Zh. Burkeev and A.T. Kazhmuratova and T.S. Zhumagaliyeva and S.I. Ali and {Herk, van}, A.M.",

year = "2012",

doi = "10.1007/s11094-012-0724-1",

language = "English",

volume = "46",

pages = "6--9",

journal = "Pharmaceutical Chemistry Journal",

issn = "0091-150X",

publisher = "Springer",

number = "1",

}

TY - JOUR

T1 - Synthesis and characterization of polyethyl cyanoacrylate nanoparticles loaded with capreomycin sulfate

AU - Zhaparova, L.

AU - Tazhbayev, Y.M.

AU - Burkeev, M.Zh.

AU - Kazhmuratova, A.T.

AU - Zhumagaliyeva, T.S.

AU - Ali, S.I.

AU - Herk, van, A.M.

PY - 2012

Y1 - 2012

N2 - Some aspects of the synthesis and characterization of polyethyl cyanoacrylate nanoparticles loaded with the antituberculosis drug capreomycin sulfate are considered in this work. Polyethyl cyanoacrylate nanoparticles containing capreomycin sulfate have been synthesized using anionic polymerization in emulsion. Optimum conditions of immobilization of the drug into the polymeric matrix have been found. It was determined that to increase the loading efficiency of the drug, it has to be added into the reaction medium after polymerization has started.

AB - Some aspects of the synthesis and characterization of polyethyl cyanoacrylate nanoparticles loaded with the antituberculosis drug capreomycin sulfate are considered in this work. Polyethyl cyanoacrylate nanoparticles containing capreomycin sulfate have been synthesized using anionic polymerization in emulsion. Optimum conditions of immobilization of the drug into the polymeric matrix have been found. It was determined that to increase the loading efficiency of the drug, it has to be added into the reaction medium after polymerization has started.

U2 - 10.1007/s11094-012-0724-1

DO - 10.1007/s11094-012-0724-1

M3 - Article

SN - 0091-150X

VL - 46

SP - 6

EP - 9

JO - Pharmaceutical Chemistry Journal

JF - Pharmaceutical Chemistry Journal

IS - 1

ER -

Synthesis and characterization of polyethyl cyanoacrylate nanoparticles loaded with capreomycin sulfate

Abstract

Access to Document

Fingerprint

Cite this