Switchable peptides

M.B. Hansen; L. Ruizendaal; D.W.P.M. Löwik; J.C.M. Hest, van

doi:10.1016/j.ddtec.2009.03.002

Switchable peptides

M.B. Hansen, L. Ruizendaal, D.W.P.M. Löwik, J.C.M. Hest, van

Research output: Contribution to journal › Review article › Academic › peer-review

4 Citations (Scopus)

Abstract

The function of peptides and proteins is strongly dependent on their three-dimensional structure, hence by controlling their conformation control over their activity can be achieved. This can be realised by the strategic manipulation of the amino acid sequence or by the introduction of functional molecules. In this review we describe the most recent work encompassing the manipulation and functionalisation of peptides within the field of switchable peptides.

Original language	English
Journal	Drug Discovery Today: Technologies
Volume	6
Issue number	1-4
DOIs	https://doi.org/10.1016/j.ddtec.2009.03.002
Publication status	Published - 2009
Externally published	Yes

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10.1016/j.ddtec.2009.03.002

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abstract = "The function of peptides and proteins is strongly dependent on their three-dimensional structure, hence by controlling their conformation control over their activity can be achieved. This can be realised by the strategic manipulation of the amino acid sequence or by the introduction of functional molecules. In this review we describe the most recent work encompassing the manipulation and functionalisation of peptides within the field of switchable peptides.",

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AU - Ruizendaal, L.

AU - Löwik, D.W.P.M.

AU - Hest, van, J.C.M.

PY - 2009

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AB - The function of peptides and proteins is strongly dependent on their three-dimensional structure, hence by controlling their conformation control over their activity can be achieved. This can be realised by the strategic manipulation of the amino acid sequence or by the introduction of functional molecules. In this review we describe the most recent work encompassing the manipulation and functionalisation of peptides within the field of switchable peptides.

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U2 - 10.1016/j.ddtec.2009.03.002

DO - 10.1016/j.ddtec.2009.03.002

M3 - Review article

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AN - SCOPUS:77957885191

VL - 6

JO - Drug Discovery Today: Technologies

JF - Drug Discovery Today: Technologies

SN - 1740-6749

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