TY - JOUR
T1 - Superficial treatment of mammalian cells using plasma needle
AU - Stoffels, E.
AU - Kieft, I.E.
AU - Sladek, R.E.J.
PY - 2003
Y1 - 2003
N2 - Interactions of a small-size, non-thermal plasma (plasma needle) with living cells in culture are studied. We have demonstrated the non-destructive character of the plasma needle: under moderate conditions (low-power and low concentration of molecular species) the plasma needle does not heat biological samples and does not induce cell death. Treatment of living cells is restricted to the cell exterior (membrane). As a result of the interactions of plasma radicals with cell adhesion molecules, cell attachment is temporarily interrupted; the loose cells can be removed, reattached or transferred. This effect may prove very useful in fine surgery, where a part of the tissue must be removed with high-precision, without damage to the adjacent cells and without inflammatory reaction
AB - Interactions of a small-size, non-thermal plasma (plasma needle) with living cells in culture are studied. We have demonstrated the non-destructive character of the plasma needle: under moderate conditions (low-power and low concentration of molecular species) the plasma needle does not heat biological samples and does not induce cell death. Treatment of living cells is restricted to the cell exterior (membrane). As a result of the interactions of plasma radicals with cell adhesion molecules, cell attachment is temporarily interrupted; the loose cells can be removed, reattached or transferred. This effect may prove very useful in fine surgery, where a part of the tissue must be removed with high-precision, without damage to the adjacent cells and without inflammatory reaction
U2 - 10.1088/0022-3727/36/23/007
DO - 10.1088/0022-3727/36/23/007
M3 - Article
VL - 36
SP - 2908
EP - 2913
JO - Journal of Physics D: Applied Physics
JF - Journal of Physics D: Applied Physics
SN - 0022-3727
IS - 23
ER -