Strong supramolecular control over protein self-assembly using a polyamine decorated β-cyclodextrin as synthetic recognition element

D.A. Uhlenheuer, L.G. Milroy, P. Neirynck, L. Brunsveld

Research output: Contribution to journalArticleAcademicpeer-review

14 Citations (Scopus)
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Abstract

The supramolecular host molecule heptakis-[6-deoxy-6-(2-aminoethylsulfanyl)]-ß-cyclodextrin provides strong control over protein self-assembly in synthetic supramolecular protein constructs. Mono-functionalization of this modified ß-cyclodextrin with a cysteine residue allows for site-selective synthetic conjugation to a protein and formation of a highly stable synthetic protein complex with a lithocholic acid conjugated protein as the interaction partner.
Original languageEnglish
Pages (from-to)18919-18922
Number of pages4
JournalJournal of Materials Chemistry
Volume21
Issue number47
DOIs
Publication statusPublished - 2011

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