Various mono- and disubstituted 2,2‘-bipyridines were synthesized in high yields and multigram scales utilizing Stille-type coupling procedures. The corresponding bromo-picoline and tributyltin-picoline building blocks were prepared from commercially available amino-picoline compounds. As first examples of metal complexes, 4,5‘-dimethyl-2,2‘-bipyridine was reacted with copper(II) and iron(II) ions and investigated as catalyst in ATRP.
Schubert, U. S., Eschbaumer, C., & Heller, M. (2000). Stille-type cross-coupling - An efficient way to various symmetrically and unsymmetrically substituted methyl-bipyridines : Toward new ATRP catalysts. Organic Letters, 2(21), 3373-3376. https://doi.org/10.1021/ol006473s