TY - JOUR
T1 - Stereochemical language in supramolecular polymer chemistry
T2 - How we can do better
AU - Palmans, Anja R.A.
AU - Meijer, E. W.
AU - Denmark, Scott E.
PY - 2021/1/4
Y1 - 2021/1/4
N2 - Stereochemical nomenclature remains a point of attention; especially now different fields in chemistry become more and more entwined. The ubiquitously used terminology “amplification of chirality” is fundamentally incorrect, as chirality cannot be amplified. Instead, we now recommend “amplification of asymmetry” as an alternative in the field of (supramolecular) polymer chemistry. Amplification of asymmetry refers to the increase of the magnitude of the asymmetry in the enantiomeric composition either at the molecular or the supramolecular level, and covers observations of nonproportional increase in optical activity in helical (supramolecular) polymers and in high enantiomeric excesses found when nonlinear effects are operative in asymmetric catalysis.
AB - Stereochemical nomenclature remains a point of attention; especially now different fields in chemistry become more and more entwined. The ubiquitously used terminology “amplification of chirality” is fundamentally incorrect, as chirality cannot be amplified. Instead, we now recommend “amplification of asymmetry” as an alternative in the field of (supramolecular) polymer chemistry. Amplification of asymmetry refers to the increase of the magnitude of the asymmetry in the enantiomeric composition either at the molecular or the supramolecular level, and covers observations of nonproportional increase in optical activity in helical (supramolecular) polymers and in high enantiomeric excesses found when nonlinear effects are operative in asymmetric catalysis.
KW - amplification of asymmetry
KW - amplification of chirality
KW - asymmetric synthesis
KW - helical polymers
KW - supramolecular polymerization
UR - http://www.scopus.com/inward/record.url?scp=85099014337&partnerID=8YFLogxK
U2 - 10.1002/pol.20200814
DO - 10.1002/pol.20200814
M3 - Article
AN - SCOPUS:85099014337
JO - Journal of Polymer Science
JF - Journal of Polymer Science
SN - 0022-3832
ER -