SpotXplore: a Cytoscape plugin for visual exploration of hotspot expression in gene regulatory networks

M.A. Westenberg, J.B.T.M. Roerdink, O.P. Kuipers, S.A.F.T. Hijum, van

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Abstract

SpotXplore is a plugin for Cytoscape for extraction and visualization of differentially expressed subnetworks (hotspots) from gene networks. The hotspot-based visualization approach enables interactive exploration of regulatory interactions in differentially expressed gene sets, and it allows a researcher to explore gene expression in direct relation to the affected cellular gene network. The hotspots provide a view beyond the commonly used metabolic pathways and gene ontologies.
Original languageEnglish
Pages (from-to)2922-2923
JournalBioinformatics
Volume26
Issue number22
DOIs
Publication statusPublished - 2010

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