SpotXplore: a Cytoscape plugin for visual exploration of hotspot expression in gene regulatory networks

M.A. Westenberg; J.B.T.M. Roerdink; O.P. Kuipers; S.A.F.T. Hijum, van

doi:10.1093/bioinformatics/btq535

SpotXplore: a Cytoscape plugin for visual exploration of hotspot expression in gene regulatory networks

M.A. Westenberg, J.B.T.M. Roerdink, O.P. Kuipers, S.A.F.T. Hijum, van

Research output: Contribution to journal › Article › Academic › peer-review

7 Citations (Scopus)

Abstract

SpotXplore is a plugin for Cytoscape for extraction and visualization of differentially expressed subnetworks (hotspots) from gene networks. The hotspot-based visualization approach enables interactive exploration of regulatory interactions in differentially expressed gene sets, and it allows a researcher to explore gene expression in direct relation to the affected cellular gene network. The hotspots provide a view beyond the commonly used metabolic pathways and gene ontologies.

Original language	English
Pages (from-to)	2922-2923
Journal	Bioinformatics
Volume	26
Issue number	22
DOIs	https://doi.org/10.1093/bioinformatics/btq535
Publication status	Published - 2010

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title = "SpotXplore: a Cytoscape plugin for visual exploration of hotspot expression in gene regulatory networks",

abstract = "SpotXplore is a plugin for Cytoscape for extraction and visualization of differentially expressed subnetworks (hotspots) from gene networks. The hotspot-based visualization approach enables interactive exploration of regulatory interactions in differentially expressed gene sets, and it allows a researcher to explore gene expression in direct relation to the affected cellular gene network. The hotspots provide a view beyond the commonly used metabolic pathways and gene ontologies.",

author = "M.A. Westenberg and J.B.T.M. Roerdink and O.P. Kuipers and {Hijum, van}, S.A.F.T.",

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SpotXplore: a Cytoscape plugin for visual exploration of hotspot expression in gene regulatory networks

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