Specific recognition of disaccharides in water by an artificial bicyclic carbohydrate receptor

Theis Reenberg, Nils Nyberg, Jens Duus, Joost L.J. van Dongen, Morten Meldal (Corresponding author)

Research output: Contribution to journalArticleAcademicpeer-review

28 Citations (Scopus)

Abstract

We present the synthesis of a peptide-based bicyclic carbohydrate receptor capable of carbohydrate recognition in 10 % deuterated acetic acid in water. The binding constants were estimated by using NMR spectroscopy, and furthermore, a series of carbohydrate complexes were studied with the use of MS (ESI) of the complex.

Original languageEnglish
Pages (from-to)5003-5009
Number of pages7
JournalEuropean Journal of Organic Chemistry
Issue number30
DOIs
Publication statusPublished - 1 Nov 2007

Keywords

  • Carbohydrate sensors
  • Combinatorial chemistry
  • Mass spectrometry
  • Molecular recognition
  • Supramolecular chemistry

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