Solvent-induced morphological transition in core-cross-linked block copolymer micelles

H. Huang, R. Hoogenboom, M.A.M. Leenen, P. Guillet, A.M. Jonas, U.S. Schubert, J.M.W. Gohy

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Microwave-assisted polymerization has been utilized to synthesize amphiphilic poly(2-ethyl-2-oxazoline-block-2-"soy alkyl"-2-oxazoline) diblock copolymers (PEtOx-PSoyOx). The amphiphilic block copolymers have been used to prepare aqueous spherical micelles consisting of a PEtOx corona and a PSoyOx core, which have been further cross-linked by UV irradiation. The morphology of these cross-linked micelles has been shown to reversibly change from spheres to short rods referred to as rice grains whenever the micelles were transferred from water into acetone, a nonselective solvent for the constituent blocks. This morphological transition has been attributed to the swelling of the slightly cross-linked PSoyOx core.
Original languageEnglish
Pages (from-to)3784-3788
JournalJournal of the American Chemical Society
Issue number11
Publication statusPublished - 2006


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