Silhouette blend rendering of anatomical structures

Systems and methods for rendering advantageous images/views of an anatomical structure, e.g., vessel structure(s), and surrounding anatomical features/structures are provided. The disclosed systems and methods combine conventional 3D x-ray rotational angiography (3DRA) with a diagnostic scan of the relevant anatomical region, e.g., a CT or MR scan, to yield a combined image/view thereof. The image includes silhouette rendering of structures and/or vessel anatomy below the CT/MRI slab, i.e., obscured vessel structures, thereby allowing clinicians and other medical/surgical staff to develop a better understanding of vessel morphology and relationships between vessel pathology and surrounding branches/anatomical structures.