Sensitivity analysis and optimal shape design for bone-prosthesis interfaces in a femoral head surface replacement

P. Vena, N.J.J. Verdonschot, R. Contro, H.W.J. Huiskes

Research output: Contribution to journalArticleAcademicpeer-review

10 Citations (Scopus)

Abstract

A numerical optimization procedure has been applied for the shape optimal design of a femoral head surface replacement. The failure modes of the prosthesis that were considered in the formulation of the objective functions concerned the interface stress magnitude and the bone remodelling activity beneath the implant. In order to find a compromising solution between different requirements demanded by the two objective functions, a two step optimization procedure has been developed. Through step I the minimization of interface stress was achieved, through step 2 the minimization of bone remodelling was achieved with constraints on interface stresses. The results obtained provided an optimal design that generates limited bone remodelling activity with controlled interface stress distribution. The computational procedure was based on the application of the finite element method, linked to a mathematical programming package and a design sensitivity analysis package.
Original languageEnglish
Pages (from-to)245-256
Number of pages12
JournalComputer Methods in Biomechanics and Biomedical Engineering
Volume3
Issue number3
DOIs
Publication statusPublished - 2000

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